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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Comparison of the agonist activity of impromidine (SK & F 92676) in anaesthetized rabbits and on the rabbit isolated fundic mucosa.

1 The actions of impromidine in vivo and in vitro have been compared on gastric acid secretion. In both preparations impromidine was more potent than histamine. 2 There were no statistically significant differences between the maximum responses to impromidine and histamine in vivo or in vitro although in vitro the maximum response to impromidine was only 67% of that to histamine. In vivo the maximum response to impromidine was significantly less than the maximum response to histamine plus mepyramine. 3 The results are discussed in the light of recent findings.[1]

References

  1. Comparison of the agonist activity of impromidine (SK & F 92676) in anaesthetized rabbits and on the rabbit isolated fundic mucosa. Curwain, B.P., Turner, N.C. Br. J. Pharmacol. (1981) [Pubmed]
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