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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Mood effects of diazepam and caffeine.

Changes in mood after administration of Diazepam and Caffeine were analyzed. Six aspects were studied: pleasantness, activation, extraversion, calmness, social orientation and control. In addition to this check list, mood ratings using magnitude estimation of selected adjectives were obtained. It was found that Diazepam decreased feelings of activation and extraversion and increased calmness. Caffeine had no clear effects on the check list, but on the magnitude estimation scale some effects opposite to those of Diazepam were observed. Men reported a higher degree of pleasantness than women after administration of Diazepam. No differences in heart rate were found. Few distinct scale values were utilized on the magnitude estimation scale and the discriminative power was found to be larger for the check list than for the magnitude estimation scale.[1]


  1. Mood effects of diazepam and caffeine. Svensson, E., Persson, L.O., Sjöberg, L. Psychopharmacology (Berl.) (1980) [Pubmed]
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