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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Rapid diagnosis of pulmonary coccidioidomycosis. Cytologic v potassium hydroxide preparations.

In 26 patients with culture-proved pulmonary coccidioidomycosis, cytologic preparations of respiratory secretions were significantly more sensitive (38.5%) than potassium hydroxide (KOH) preparations (15.4%) in identifying spherules of Coccidioides immitis. Those patients able to produce sputum or having multiple-lobe pneumonitis on chest roentgenogram appeared to be more likely to have spherules identified in the sputum by either technique. In the absence of sputum production or multiple-lobe pneumonitis, neither cytologic nor KOH preparations were likely to disclose spherules. Because of its greater sensitivity, a cytologic preparation should be examined in addition to a KOH preparation when pulmonary coccidioidomycosis is a clinical consideration.[1]

References

  1. Rapid diagnosis of pulmonary coccidioidomycosis. Cytologic v potassium hydroxide preparations. Warlick, M.A., Quan, S.F., Sobonya, R.E. Arch. Intern. Med. (1983) [Pubmed]
 
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