Disease relevance of potassium hydroxide

• Rapid diagnosis of pulmonary coccidioidomycosis. Cytologic v potassium hydroxide preparations [1].
• RESEARCH DESIGN AND METHODS: Nail samples from 184 diabetic patients who exhibited symptoms consistent with toenail onychomycosis were screened for dermatophyte fungal infection using DTM, potassium hydroxide evaluation, and central mycology laboratory culture tests [2].
• Tinea unguium was defined as a positive direct examination with potassium hydroxide and culture of the etiological agent from subjects with clinically abnormal nails [3].
• In 77 patients with acute Candida vaginitis, the SLA test revealed a positive reaction in 56 patients, reflecting a sensitivity of 72.7%, lower than that observed with the 10% potassium hydroxide microscopic examination (sensitivity 90%) [4].
• Our aim was to assess the specificity of 40% potassium hydroxide preparations in diagnosing bacterial pneumonia in patients with ARDS and suspected pneumonia [5].

High impact information on potassium hydroxide

• CM are extracted from the myocardium and blood by digestion with potassium hydroxide and subsequent microfiltration [6].
• Elastin peptides prepared by alcoholic potassium hydroxide degradation of highly purified fibrous elastin from bovine ligamentum nuchae (kappa-elastin) were shown to act on the ion channels of human monocytes, aorta smooth muscle cells, and skin fibroblasts [7].
• In patients with blastomycotic arthritis, cytologic examination of synovial fluid can add to the diagnostic yield of synovial fluid fungal cultures and potassium hydroxide preparations [8].
• The distribution of STn and Tn in normal and malignant epithelium has been studied in detail by a combination of mucin-, lectin-, and immunohistochemistry with and without pretreatment with potassium hydroxide (KOH), neuraminidase, and KOH-neuraminidase [9].
• RAST analyses of sera from 24 allergic bakers demonstrated that the albumin fraction of flour is clearly allergenic (as found in previous studies), but in addition, major IgE-binding proteins were found in the other three fractions (globulin, gliadin, and glutenin) when potassium hydroxide was the solvent (but not with water) [10].

Chemical compound and disease context of potassium hydroxide

• Twenty cases of resected specimens of carcinoma and/or dysplasia complicating ulcerative colitis were histochemically investigated by the periodic acid-thionein Schiff/potassium hydroxide/periodic acid-Schiff (PAT/KOH/PAS) staining method to see mucin characteristics of carcinoma, dysplasia, and the background mucosa of these lesions [11].
• Application of 1% potassium hydroxide (KOH) reduced subsequent development of anthralin inflammation without loss of its therapeutic effect on psoriasis [12].
• Sulconazole nitrate 1% cream applied twice daily was compared with its vehicle in the treatment of 229 patients with chronic moccasin-type tinea pedis confirmed by positive results of a potassium hydroxide preparation [13].
• Solutions of potassium hydroxide and sodium hydroxide with concentrations between 0.5% and 4% were found to produce mucoid and sticky suspensions when added in drops, using a bacteriological loop, to smears of 609 strains of gram-negative bacteria on glass slides [14].
• Among all children showing symptoms suggestive of scalp ringworm, hair stumps and scales were collected and exposed to direct microscopic examination using 30% potassium hydroxide solution, and cultivation on Sabouraud's dextrose agar with or without actidione [15].

Biological context of potassium hydroxide

• The N-acetyl group of 4 was removed by hydrolysis with ethanolic potassium hydroxide to form 1-O-hexadecyl-2-O-methyl-3-O-(2'-amino-2'-deoxy-beta-D-glucopyranosyl)- sn-glycerol (5) [16].
• Radiochemical yields were increased to 40-50% when the alkylation of 2 with [11C]methyl iodide was performed in dimethyl sulfoxide using solid potassium hydroxide as a base [17].
• Wound healing after potassium hydroxide and surgical gingivectomy in rats [18].
• Selective hydrogenation of 7 followed by hydrolysis in alcoholic potassium hydroxide yielded (25R)-3beta,26-dihydroxy-5alpha-cholest-8(14)-en-15-one (1) [19].
• STUDY DESIGN: A total of 2929 women at 10 centers were studied at 24 and 28 weeks' gestation by Gram stain of vaginal smear, wet mount, and 10% potassium hydroxide preparations to detect vaginal infections [20].

Anatomical context of potassium hydroxide

• Three patients had negative 10% potassium hydroxide smears, and 2 had negative synovial fluid cultures [8].
• The soft tissue was then digested, using 40% potassium hydroxide, to obtain detailed casts of the eyelid arteries, arterioles, and capillaries [21].
• Intact antibiotics which contain the MTT moiety did not cause an inhibition of yeast ALDH unless the antibiotics were first treated with potassium hydroxide and then incubated with microsomes [22].
• Potassium hydroxide (KOH) preparations for elastin fibers on sputum obtained from 80 patients seen over a four-month period at two Cleveland hospitals were performed [23].
• The cross-links remained in the cell wall of the elongated region after treatment with SDS electrophoresis sample buffer and treatment with 4% potassium hydroxide [24].

Associations of potassium hydroxide with other chemical compounds

• Following hydrolysis of possible conjugates, triclosan is extracted with n-hexane/acetone, partitioned into alcoholic potassium hydroxide, and converted into its pentafluorobenzoyl ester [25].
• Treatment of 7a with tertbutyl hydroperoxide in the presence of potassium hydroxide afforded a mixture of benzocarbaporphyrins 9a-c. These tetraphenylcarbaporphyrins were fully aromatic by NMR spectroscopy and gave typical porphyrin-type UV/Vis spectra with a strong Soret band near 446 nm [26].
• Polyuronides were extracted from purified yeast and mycelial walls of Mucor rouxii by sequential treatments with lithium chloride and potassium hydroxide and were fractionated by ion-exchange chromatography on DEAE-Sephadex [27].
• Quality control slide for potassium hydroxide and cellufluor fungal preparations [28].
• A comparison of the fraction of resins was performed by re-fractionating with modified silica (with potassium hydroxide and hydrochloric acid), or with ion exchange resins (Amberlyst A-27 and A-15), being isolated the basic and neutral compounds, that were analyzed by GC-MS in the scan and selected ion monitoring modes [29].

Gene context of potassium hydroxide

• Colonic mucosa of the left colon in 41 patients with familial polyposis coli (FPC) was stained by a periodic acid-thionin Schiff/potassium hydroxide/periodic acid-Schiff method in which the normal colonic mucosa usually stained red and carcinoma stained blue or purple [30].
• This type of molecule gives a positive staining after potassium hydroxide/periodate borohydride (KOH/PBT) treatment [31].
• The supernatant solution was neutralized by potassium hydroxide solution and thymosin beta 4 was measured by HPLC without further manipulations [32].
• After neutralization by potassium hydroxide the supernatant solution was used for determining thymosin beta 4 by reverse-phase HPLC without further manipulations [33].
• FPIA false negatives occurred with bleach (PCP and THC-COOH assays) and potassium hydroxide (PCP assay) adulterants [34].

Analytical, diagnostic and therapeutic context of potassium hydroxide

• Samples were then digested with potassium hydroxide and microspheres recovered by vacuum filtration, with an additional label of FM as the internal standard [35].
• Constant flow perfusion of skeletal and cardiac muscle by a modified Batson's compound for anatomical casting made available rigid three-dimensional replicas of the microvasculature which shrank less than 1% when the tissue was digested with potassium hydroxide [36].
• The latter is hydrolyzed, without isolation, with potassium hydroxide in tetrahydrofuran-methanol to give epicholesterol, which is obtained in pure form by preparative thin-layer chromatography [37].
• The purpose of the present study was to examine three modifications to the processing of fecal specimens for light microscopy (LM) examination for microsporidian spores: the use of pretreatment with potassium hydroxide, modified centrifugation conditions, and a modified staining technique [38].
• A potassium hydroxide examination and assessment of scaling, erythema, pruritus, and global condition were performed at baseline and at 4 weeks after treatment [39].

References