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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Pneumonia

 
 
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Disease relevance of Pneumonia

 

Psychiatry related information on Pneumonia

 

High impact information on Pneumonia

 

Chemical compound and disease context of Pneumonia

 

Biological context of Pneumonia

 

Anatomical context of Pneumonia

 

Gene context of Pneumonia

  • OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation [28].
  • Treatment of mice with IL-12 at the time of a second antigen challenge also prevented airway hyperresponsiveness and significantly reduced numbers of BAL inflammatory cells, reflecting the ability of IL-12 to inhibit responses associated with ongoing antigen-induced pulmonary inflammation [29].
  • In contrast, Ptgs1-deficient mice had pancreatitis and pulmonary inflammation, which was as severe or, in some instances, more severe than in the wild-type mice [30].
  • Here we report that Runx3 knockout (KO) mice develop spontaneous eosinophilic lung inflammation associated with airway remodeling and mucus hypersecretion [31].
  • These data suggest that a TM mutation that impairs APC generation results in uncontrolled lung inflammation during tuberculosis [32].
 

Analytical, diagnostic and therapeutic context of Pneumonia

References

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  22. In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. Blackwell, T.S., Blackwell, T.R., Holden, E.P., Christman, B.W., Christman, J.W. J. Immunol. (1996) [Pubmed]
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  28. OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation. Salek-Ardakani, S., Song, J., Halteman, B.S., Jember, A.G., Akiba, H., Yagita, H., Croft, M. J. Exp. Med. (2003) [Pubmed]
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