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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Heart imaging with cationic complexes of technetium.

The cationic technetium-99 complex trans-[99TC(dmpe)2Cl2]+, where dmpe is bis(1,2-dimethylphosphino)ethane or (CH3)2P-CH2-P(CH3)2, has been prepared and characterized by single-crystal, x-ray structural analysis. The technetium-99m analog, trans-(99mTc(dmpe) 2Cl2]+, has also been prepared and shown to yield excellent gamma-ray images of the heart. The purposeful design, characterization, and synthesis of this technetium-99m radiopharmaceutical represents a striking application of fundamental inorganic chemistry to a problem in applied nuclear medicine.[1]

References

  1. Heart imaging with cationic complexes of technetium. Deutsch, E., Bushong, W., Glavan, K.A., Elder, R.C., Sodd, V.J., Scholz, K.L., Fortman, D.L., Lukes, S.J. Science (1981) [Pubmed]
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