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MeSH Review

Nuclear Medicine

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Disease relevance of Nuclear Medicine


Psychiatry related information on Nuclear Medicine


High impact information on Nuclear Medicine


Chemical compound and disease context of Nuclear Medicine


Biological context of Nuclear Medicine


Anatomical context of Nuclear Medicine


Associations of Nuclear Medicine with chemical compounds


Gene context of Nuclear Medicine

  • The high level expression of somatostatin receptors (SSTR) on various tumor cells has provided the molecular basis for successful use of radiolabeled octreotide / lanreotide analogs as tumor tracers in nuclear medicine [33].
  • Thus, radiolabeled BN or BN analogs may prove to be specific tracers for diagnostic and therapeutic targeting of GRP-r-positive tumors in nuclear medicine [34].
  • Six European nuclear medicine centres performed immunoscintigraphy first retrospectively in 34 patients using indium-111-labelled carcinoembryonic antigen (CEA)-specific and/or 19-9 F(ab')2 fragments [35].
  • Different peptide receptors like somatostatin, bombesin/GRP or VIP are (over)expressed on cancer cells, and are therefore an ideal target for the diagnosis and therapy in nuclear medicine with radiolabeled peptides [36].
  • We therefore conclude that [99mTc(I)-PADA-AVA]bombesin (7-14) might have promising characteristics for applications in nuclear medicine, namely for diagnosis of GRP receptor overexpressing tumors [37].

Analytical, diagnostic and therapeutic context of Nuclear Medicine


  1. Imaging of estrogen receptors in primary and metastatic breast cancer patients with iodine-123-labeled Z-MIVE. Rijks, L.J., Bakker, P.J., van Tienhoven, G., Noorduyn, L.A., Boer, G.J., Rietbroek, R.C., Taat, C.W., Janssen, A.G., Veenhof, C.H., van Royen, E.A. J. Clin. Oncol. (1997) [Pubmed]
  2. Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical study. Parliament, M.B., Chapman, J.D., Urtasun, R.C., McEwan, A.J., Golberg, L., Mercer, J.R., Mannan, R.H., Wiebe, L.I. Br. J. Cancer (1992) [Pubmed]
  3. Influences on renal function in chronic spinal cord injured patients. Weld, K.J., Wall, B.M., Mangold, T.A., Steere, E.L., Dmochowski, R.R. J. Urol. (2000) [Pubmed]
  4. Occurrence of a pulmonary carcinoid following allogeneic stem cell transplantation for chronic myelogenous leukemia: a case report. Fiebiger, W., Kurtaran, A., Novotny, C., Kainberger, F., Dekan, G., Raderer, M. Ann. Hematol. (2003) [Pubmed]
  5. Nuclear medicine evaluation of hypertension. Fine, E.J. Urologic radiology. (1992) [Pubmed]
  6. FDG PET imaging in patients with pathologically verified dementia. Hoffman, J.M., Welsh-Bohmer, K.A., Hanson, M., Crain, B., Hulette, C., Earl, N., Coleman, R.E. J. Nucl. Med. (2000) [Pubmed]
  7. Team effort: the nuclear medicine decision making process. Part II. Tsuchiyama, S. Administrative radiology : AR. (1991) [Pubmed]
  8. Assessment of axillary lymph node involvement in breast cancer patients with positron emission tomography using radiolabeled 2-(fluorine-18)-fluoro-2-deoxy-D-glucose. Avril, N., Dose, J., Jänicke, F., Ziegler, S., Römer, W., Weber, W., Herz, M., Nathrath, W., Graeff, H., Schwaiger, M. J. Natl. Cancer Inst. (1996) [Pubmed]
  9. Interleukin-2 induces profound reversible cholestasis: a detailed analysis in treated cancer patients. Fisher, B., Keenan, A.M., Garra, B.S., Steinberg, S.M., White, D.E., DiBisceglie, A.M., Hoofnagle, J.H., Yolles, P., Rosenberg, S.A., Lotze, M.T. J. Clin. Oncol. (1989) [Pubmed]
  10. The role of nuclear medicine in the evaluation of neuropsychiatric systemic lupus erythematosus: comment on the article by Sibbitt et al. Colamussi, P., Govoni, M. Arthritis Rheum. (2000) [Pubmed]
  11. Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. Harrington, K.J., Mohammadtaghi, S., Uster, P.S., Glass, D., Peters, A.M., Vile, R.G., Stewart, J.S. Clin. Cancer Res. (2001) [Pubmed]
  12. Comparison between nocturnal nasal positive pressure ventilation combined with oxygen therapy and oxygen monotherapy in patients with severe COPD. Lin, C.C. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  13. Case report: uptake of pentavalent technetium-99m dimercaptosuccinic acid by pigmented villonodular synovitis: comparison with computed tomography, magnetic resonance imaging and gallium-67 scintigraphy. Kobayashi, H., Kotoura, Y., Hosono, M., Sakahara, H., Yamamuro, T., Endo, K., Konishi, J. The British journal of radiology. (1994) [Pubmed]
  14. Nuclear medicine studies in metabolic bone disease. Hain, S.F., Fogelman, I. Seminars in musculoskeletal radiology. (2002) [Pubmed]
  15. Bone scan: a useful test for evaluating patients with low back pain. Collier, B.D., Kir, K.M., Mills, B.J., Patel, N.C., Pochis, W.T., Onsel, C., Liu, Y., Turoglu, H.T. Skeletal radiology. (1990) [Pubmed]
  16. Prominent small bowel Ga-67 uptake associated with Yersinial and tuberculous enterocolitis. Brophey, M., Lamki, L., Barron, B., Shah, S. Clinical nuclear medicine. (1995) [Pubmed]
  17. Nuclear medicine studies in the differential diagnosis of diseases with spinal involvement. Didion, K., Nägele-Wöhrle, B., Schaub, T., Hahn, K. Neurosurgical review. (1990) [Pubmed]
  18. Quantitative SPECT reconstruction of iodine-123 data. Gilland, D.R., Jaszczak, R.J., Greer, K.L., Coleman, R.E. J. Nucl. Med. (1991) [Pubmed]
  19. The "well tempered" diuretic renogram: a standard method to examine the asymptomatic neonate with hydronephrosis or hydroureteronephrosis. A report from combined meetings of The Society for Fetal Urology and members of The Pediatric Nuclear Medicine Council--The Society of Nuclear Medicine. Conway, J.J., Maizels, M. J. Nucl. Med. (1992) [Pubmed]
  20. Impressions and clinical consequences of a multidisciplinary congress: neurology and nuclear medicine. 10th seminar of Serre Chevalier, France, 24-30 January, 1999 under the auspices of the French Society of Biophysics and Nuclear Medicine. Als, C., Fincker, F., Buchler, P., Rauchs, P., Schroeder, M., Bräutigam, P., Hupez, P. European journal of nuclear medicine. (1999) [Pubmed]
  21. Genotoxic and mutagenic effects of the diagnostic use of thallium-201 in nuclear medicine. Kelsey, K.T., Donohoe, K.J., Baxter, B., Memisoglu, A., Little, J.B., Caggana, M., Liber, H.L. Mutat. Res. (1991) [Pubmed]
  22. Evaluation of the effect of mitomycin-C on the bioavailability of technetium-99m-labelled sodium pyrophosphate in mice. Gomes, M.L., de Mattos, D.M., Freitas, R.S., Diré, G.F., Lima, E.A., Souza, S.M., Bernardo-Filho, M. Cell. Mol. Biol. (Noisy-le-grand) (2002) [Pubmed]
  23. Internal contamination of laboratory personnel by 131I1. Nishiyama, H., Lukes, S.J., Mayfield, G., Grossman, L.W. Radiology. (1980) [Pubmed]
  24. The effect of drugs on the labeling of blood elements with technetium-99m. Braga, A.C., Oliveira, M.B., Feliciano, G.D., Reiniger, I.W., Oliveira, J.F., Silva, C.R., Bernardo-Filho, M. Curr. Pharm. Des. (2000) [Pubmed]
  25. In vivo exposure of human lymphocytes to technetium-99m in nuclear medicine patients does not induce detectable genetic effects. Kelsey, K.T., Donohoe, K.J., Memisoglu, A., Baxter, B., Caggana, M., Liber, H.L. Mutat. Res. (1991) [Pubmed]
  26. [11C]Methionine positron emission tomography for patients with persistent or recurrent hyperparathyroidism after surgery. Cook, G.J., Wong, J.C., Smellie, W.J., Young, A.E., Maisey, M.N., Fogelman, I. Eur. J. Endocrinol. (1998) [Pubmed]
  27. Nuclear medicine and infection detection: the relative effectiveness of imaging with 111In-oxine-, 99mTc-HMPAO-, and 99mTc-stannous fluoride colloid-labeled leukocytes and with 67Ga-citrate. Hughes, D.K. Journal of nuclear medicine technology. (2003) [Pubmed]
  28. Procedure guideline for pediatric sedation in nuclear medicine. Society of Nuclear Medicine. Mandell, G.A., Cooper, J.A., Majd, M., Shalaby-Rana, E.I., Gordon, I. J. Nucl. Med. (1997) [Pubmed]
  29. Scintigraphic evaluation of pancreatic transplants using technetium-99m-sestamibi. Elgazzar, A.H., Munda, R., Fernandez-Ulloa, M., Clark, J., Ryan, J.R., Hughes, J.A. J. Nucl. Med. (1995) [Pubmed]
  30. The relevance of basic technetium chemistry to nuclear medicine. Jones, A.G., Davison, A. J. Nucl. Med. (1982) [Pubmed]
  31. Variability in the interpretation of dimercaptosuccinic acid scintigraphy after urinary tract infection in children. Craig, J.C., Irwig, L.M., Howman-Giles, R.B., Uren, R.F., Bernard, E.J., Knight, J.F., Sureshkumar, P., Roy, L.P. J. Nucl. Med. (1998) [Pubmed]
  32. Uptake of gallium-67 in transfected cells and tumors absent or enriched in the transferrin receptor. Luttropp, C.A., Jackson, J.A., Jones, B.J., Sohn, M.H., Lynch, R.E., Morton, K.A. J. Nucl. Med. (1998) [Pubmed]
  33. Experience with indium-111 and yttrium-90-labeled somatostatin analogs. Virgolini, I., Traub, T., Novotny, C., Leimer, M., Füger, B., Li, S.R., Patri, P., Pangerl, T., Angelberger, P., Raderer, M., Burggasser, G., Andreae, F., Kurtaran, A., Dudczak, R. Curr. Pharm. Des. (2002) [Pubmed]
  34. GRP receptor-targeted PET of a rat pancreas carcinoma xenograft in nude mice with a 68Ga-labeled bombesin(6-14) analog. Schuhmacher, J., Zhang, H., Doll, J., Mäcke, H.R., Matys, R., Hauser, H., Henze, M., Haberkorn, U., Eisenhut, M. J. Nucl. Med. (2005) [Pubmed]
  35. Multi-centre immunoscintigraphic study using indium-111-labelled CEA-specific and/or 19-9 monoclonal antibody F(ab')2 fragments. Chetanneau, A., Baum, R.P., Lehur, P.A., Liehn, J.C., Perkins, A.C., Bares, R., Bourguet, P., Herry, J.Y., Saccavini, J.C., Chatal, J.F. European journal of nuclear medicine. (1990) [Pubmed]
  36. Cholecystokinin-B (CCK-B)/gastrin receptor targeting peptides for staging and therapy of medullary thyroid cancer and other CCK-B receptor expressing malignancies. Béhé, M., Behr, T.M. Biopolymers (2002) [Pubmed]
  37. In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors. La Bella, R., Garcia-Garayoa, E., Langer, M., Bläuenstein, P., Beck-Sickinger, A.G., Schubiger, P.A. Nucl. Med. Biol. (2002) [Pubmed]
  38. Evaluation of methods to detect interhemispheric asymmetry on cerebral perfusion SPECT: application to epilepsy. Aubert-Broche, B., Jannin, P., Biraben, A., Bernard, A.M., Haegelen, C., Le Jeune, F.P., Gibaud, B. J. Nucl. Med. (2005) [Pubmed]
  39. Radioimmunotherapy and NHL: nuclear medicine on the oncology team. Knight, N. J. Nucl. Med. (2002) [Pubmed]
  40. Pediatric imaging: sedation with an injection formulation modified for rectal administration. Nguyen, M.T., Greenberg, S.B., Fitzhugh, K.R., Glasier, C.M. Radiology. (2001) [Pubmed]
  41. Radiation dose to technicians per nuclear medicine procedure: comparison between technetium-99m, gallium-67, and iodine-131 radiotracers and fluorine-18 fluorodeoxyglucose. Chiesa, C., De Sanctis, V., Crippa, F., Schiavini, M., Fraigola, C.E., Bogni, A., Pascali, C., Decise, D., Marchesini, R., Bombardieri, E. European journal of nuclear medicine. (1997) [Pubmed]
  42. The clinical value of nuclear medicine in the assessment of irradiation-induced and anthracycline-associated cardiac damage. Goethals, I., De Winter, O., De Bondt, P., De Sutter, J., Dierckx, R., Van De Wiele, C. Ann. Oncol. (2002) [Pubmed]
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