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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Intraventricular calcitonin inhibits gastric acid secretion.

Parenteral and intracerebroventricular administration of calcitonin in rats resulted in the suppression of gastric acid secretion. This suppression also occurred in rats with insulin-induced hypoglycemia and after the administration of thyrotropin-releasing hormone. Intracerebroventricularly administered calcitonin was 1000 times more effective than parenterally administered calcitonin in suppressing gastric acid secretion. Calcitonin also inhibited the development of stress-induced ulcers in rats.[1]


  1. Intraventricular calcitonin inhibits gastric acid secretion. Morley, J.E., Levine, A.S., Silvis, S.E. Science (1981) [Pubmed]
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