Gene Review:
Trh - thyrotropin releasing hormone
Rattus norvegicus
Synonyms:
Pro-TRH, Pro-thyrotropin-releasing hormone, Prothyroliberin, THR, TRH01, ...
- Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways. Evidence of a role for early tyrosine phosphorylation. Ohmichi, M., Sawada, T., Kanda, Y., Koike, K., Hirota, K., Miyake, A., Saltiel, A.R. J. Biol. Chem. (1994)
- Vasopressin and oxytocin release as influenced by thyrotropin-releasing hormone in euhydrated and dehydrated rats. Ciosek, J. J. Physiol. Pharmacol. (2002)
- Thyrotropin releasing hormone injected into the nucleus accumbens septi selectively increases face grooming in rats. Gargiulo, P.A. Braz. J. Med. Biol. Res. (1996)
- Thyrotropin-releasing hormone is induced in the left ventricle of rats with heart failure and can provide inotropic support to the failing heart. Jin, H., Fedorowicz, G., Yang, R., Ogasawara, A., Peale, F., Pham, T., Paoni, N.F. Circulation (2004)
- Regulation of thyrotropin-releasing hormone in the posterior pituitary. Rondeel, J.M., Klootwijk, W., Linkels, E., van Haasteren, G.A., de Greef, W.J., Visser, T.J. Neuroendocrinology (1995)
- JTP-4819: a novel prolyl endopeptidase inhibitor with potential as a cognitive enhancer. Toide, K., Iwamoto, Y., Fujiwara, T., Abe, H. J. Pharmacol. Exp. Ther. (1995)
- Changes in TRH and its degrading enzyme pyroglutamyl peptidase II, during the development of amygdaloid kindling. de Gortari, P., Fernández-Guardiola, A., Martinez, A., Cisneros, M., Joseph-Bravo, P. Brain Res. (1995)
- Thyrotropin-releasing hormone and dementia. Sunderland, T., Mellow, A.M., Gross, M., Cohen, R.M., Tariot, P.N., Newhouse, P.A., Murphy, D.L. The American journal of psychiatry. (1986)
- Adenohypophyseal degradation of thyrotropin releasing hormone regulated by thyroid hormones. Bauer, K. Nature (1987)
- Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum. Imai, A., Gershengorn, M.C. Nature (1987)
- Thyrotropin-releasing hormone--CNS action to stimulate gastric acid secretion. Taché, Y., Vale, W., Brown, M. Nature (1980)
- Dopamine stimulates the degradation of gonadotropin releasing hormone by rat synaptosomes. Marcano de Cotte, D., De Menezes, C.E., Bennett, G.W., Edwardson, J.A. Nature (1980)
- An analogue of creatine increases TRH-stimulated prolactin secretion and phosphoinositide hydrolysis in rat pituitary tumor cells. Prysor-Jones, R.A., Silverlight, J.J., Whitley, G.S., Jenkins, J.S. Mol. Cell. Endocrinol. (1988)
- Changes of cell morphology and prolactin secretion induced by 2-Br-alpha-ergocryptine, estradiol, and thyrotropin-releasing hormone in rat anterior pituitary cells in culture. Antakly, T., Pelletier, G., Zeytinoglu, F., Labrie, F. J. Cell Biol. (1980)
- Response of hypothalamic peptide mRNAs to thyroidectomy. Ceccatelli, S., Giardino, L., Calzá, L. Neuroendocrinology (1992)
- Calcitriol attenuates the thyrotropin-releasing hormone-stimulated inositol phosphate production in clonal rat pituitary (GH4C1) cells. Sørnes, G., Haug, E., Torjesen, P.A. Mol. Cell. Endocrinol. (1993)
- Molecular mechanisms of phorbol ester, thyrotropin-releasing hormone, and growth factor stimulation of prolactin gene transcription. Murdoch, G.H., Waterman, M., Evans, R.M., Rosenfeld, M.G. J. Biol. Chem. (1985)
- Overproduction of a Ca(2+)-independent protein kinase C isozyme, nPKC epsilon, increases the secretion of prolactin from thyrotropin-releasing hormone-stimulated rat pituitary GH4C1 cells. Akita, Y., Ohno, S., Yajima, Y., Konno, Y., Saido, T.C., Mizuno, K., Chida, K., Osada, S., Kuroki, T., Kawashima, S. J. Biol. Chem. (1994)
- Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways. Thomson, A.M., Rogers, J.T., Leedman, P.J. J. Biol. Chem. (2000)
- Thyroid stimulating hormone and prolactin secretion: reduced sensitivity to TRH-stimulated prolactin release after midpregnancy in rats. Bridges, R.S., Terkel, J., Sawyer, C.H. Proc. Soc. Exp. Biol. Med. (1983)
- Thyroidectomy induces Fos-like immunoreactivity within thyrotropin-releasing hormone-expressing neurons located in the paraventricular nucleus of the adult rat hypothalamus. Koibuchi, N., Gibbs, R.B., Suzuki, M., Pfaff, D.W. Endocrinology (1991)
- Corticotropin-releasing factor acts on the brain to reduce gastric contractility. Garrick, T., Veiseh, A., Taché, Y., Weiner, H. Psychotherapy and psychosomatics. (1987)
- Effects of thyrotropin-releasing hormone on prolactin, growth hormone and corticosterone secretions in adult male rats treated with pentobarbital or morphine. Collu, R., Clermont, M.J., Ducharme, J.R. Eur. J. Pharmacol. (1976)
- Thyrotropin-releasing hormone-induced spike and plateau in cytosolic free Ca2+ concentrations in pituitary cells. Relation to prolactin release. Albert, P.R., Tashjian, A.H. J. Biol. Chem. (1984)
- Regulation of Ca2+-dependent cyclic AMP accumulation and Ca2+ metabolism in intact pituitary tumor cells by modulators of prolactin production. Brostrom, M.A., Brostrom, C.O., Brotman, L.A., Green, S.S. Mol. Pharmacol. (1983)
- CRF microinjected into the dorsal vagal complex inhibits TRH analog- and kainic acid-stimulated gastric contractility in rats. Heymann-Mönnikes, I., Taché, Y., Trauner, M., Weiner, H., Garrick, T. Brain Res. (1991)
- Thyrotropin-releasing hormone (TRH) stimulates biphasic elevation of cytoplasmic free calcium in GH3 cells. Further evidence that TRH mobilizes cellular and extracellular Ca2+. Gershengorn, M.C., Thaw, C. Endocrinology (1985)
- Regulation of thyrotropin-releasing hormone binding by monovalent cations and guanyl nucleotides. Hinkle, P.M., Kinsella, P.A. J. Biol. Chem. (1984)
- Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices. Charli, J.L., Mendez, M., Vargas, M.A., Cisneros, M., Assai, M., Joseph-Bravo, P., Wilk, S. Neuropeptides (1989)
- Analysis of the thyrotropin-releasing hormone-degrading ectoenzyme by site-directed mutagenesis of cysteine residues. Cys68 is involved in disulfide-linked dimerization. Papadopoulos, T., Heuer, H., Bauer, K. Eur. J. Biochem. (2000)
- GH4 pituitary cell variants selected as nonresponsive to thyrotropin-releasing hormone-enhanced substratum adhesion are nonresponsive to epidermal growth factor: evidence for a common signaling defect. Ramsdell, J.S., Tashjian, A.H. J. Cell. Physiol. (1989)
- Thyrotropin-releasing hormone increases the levels of c-fos and beta-actin mRNA in GH3/B6 pituitary tumor cells. Weisman, A.S., Tixier-Vidal, A., Gourdji, D. In Vitro Cell. Dev. Biol. (1987)
- Estrogen receptor-beta, but not estrogen receptor-alpha, is expressed in prolactin neurons of the female rat paraventricular and supraoptic nuclei: comparison with other neuropeptides. Suzuki, S., Handa, R.J. J. Comp. Neurol. (2005)
- Effects of lordosis-relevant neuropeptides on midbrain periaqueductal gray neuronal activity in vitro. Ogawa, S., Kow, L.M., Pfaff, D.W. Peptides (1992)
- Thyrotropin-releasing hormone gene expression in cultured anterior pituitary cells: role of gender. Bruhn, T.O., Rondeel, J.M., Bolduc, T.G., Jackson, I.M. Neuroendocrinology (1995)
- Multiple prolactin-releasing activity in the bovine hypothalamic extract. Nakamura, K., Sato, F., Yasuda, N., Kubokawa, M. Horm. Metab. Res. (2000)
- Distinct patterns of cytoplasmic protein phosphorylation related to regulation of synthesis and release of prolactin by GH cells. Sobel, A., Tashjian, A.H. J. Biol. Chem. (1983)
- Cocaine- and amphetamine-regulated transcript co-contained in thyrotropin-releasing hormone (TRH) neurons of the hypothalamic paraventricular nucleus modulates TRH-induced prolactin secretion. Raptis, S., Fekete, C., Sarkar, S., Rand, W.M., Emerson, C.H., Nagy, G.M., Lechan, R.M. Endocrinology (2004)