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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Outcome after laminectomy for lumbar spinal stenosis. Part I: Clinical correlations.

All patients who underwent decompressive lumbar laminectomy in the Washtenaw County, Michigan metropolitan area during a 7-year period were studied for the purpose of defining long-term outcome, clinical correlations, and the need for subsequent fusion. Outcome was determined by questionnaire and physical examination from a cohort of 119 patients with an average follow-up evaluation interval of 4.6 years. Patients graded their outcome as much improved (37%), somewhat improved (29%), unchanged (17%), somewhat worse (5%), and much worse (12%) compared to their condition before surgery. Poor outcome correlated with the need for additional surgery, but there were few additional significant correlations. No patient had a lumbar fusion during the study interval. The outcome after laminectomy was found to be less favorable than previously reported, based on a patient questionnaire administered to an unbiased patient population. Further randomized, controlled trials are therefore necessary to determine the efficacy of lumbar fusion as an adjunct to decompressive lumbar laminectomy.[1]


  1. Outcome after laminectomy for lumbar spinal stenosis. Part I: Clinical correlations. Tuite, G.F., Stern, J.D., Doran, S.E., Papadopoulos, S.M., McGillicuddy, J.E., Oyedijo, D.I., Grube, S.V., Lundquist, C., Gilmer, H.S., Schork, M.A. J. Neurosurg. (1994) [Pubmed]
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