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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

PART1  -  prostate androgen-regulated transcript 1...

Homo sapiens

Synonyms: DKFZP586D0823, NCRNA00206
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Disease relevance of PART1


Psychiatry related information on PART1

  • SETTINGS AND PARTICIPANTS: Part of the sample of subjects with eating disorders and all of the controls took part in a prevalence study carried out in 2 randomly selected areas of Padua [6].
  • The characteristic pathological abnormalities and its implications for Alzheimer's disease will be discussed in Part II of this article [7].
  • Anger attacks in unipolar depression, Part 1: Clinical correlates and response to fluoxetine treatment [8].
  • Revising and assessing axis II, Part II: toward an empirically based and clinically useful classification of personality disorders [9].
  • METHOD: Part I: Three hundred sixty-eight smokers who enrolled in a smoking cessation treatment study completed baseline self-rating scales [10].

High impact information on PART1


Chemical compound and disease context of PART1


Biological context of PART1


Anatomical context of PART1


Associations of PART1 with chemical compounds

  • In Part I of this article, the naturally evolved protein framework of lactate dehydrogenase is investigated by genetically introduced modifications which reveal the structural basis of its catalytic and substrate-binding properties [27].
  • In Part II, the conclusions are used in the design and synthesis of two modified forms of the enzyme; one in which the substrate specificity is shifted to produce a more effective malate dehydrogenase than that isolated from the host organism and one which no longer requires its allosteric activator (fructose 1,6-bisphosphate) [28].
  • Cholesterol screening in asymptomatic adults, revisited. Part 2 [29].
  • Myocardial preconditioning. Part of the adenosine revival [30].
  • In Part II, 67 patients with unexplained postoperative fever were given indomethacin (100 mg per day) or placebo for 7 days by a randomized, double-blind protocol [31].

Physical interactions of PART1


Other interactions of PART1


Analytical, diagnostic and therapeutic context of PART1


  1. PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12. Lin, B., White, J.T., Ferguson, C., Bumgarner, R., Friedman, C., Trask, B., Ellis, W., Lange, P., Hood, L., Nelson, P.S. Cancer Res. (2000) [Pubmed]
  2. Ovarian cancer, Part II. Barber, H.R. CA: a cancer journal for clinicians. (1980) [Pubmed]
  3. Brain tumor. Part 2. Black, P.M. N. Engl. J. Med. (1991) [Pubmed]
  4. Herpesvirus infections of pregnancy. Part II: Herpes simplex virus and varicella-zoster virus infections. Stagno, S., Whitley, R.J. N. Engl. J. Med. (1985) [Pubmed]
  5. Herpesvirus infections of pregnancy. Part I: Cytomegalovirus and Epstein-Barr virus infections. Stagno, S., Whitley, R.J. N. Engl. J. Med. (1985) [Pubmed]
  6. Perinatal factors and the risk of developing anorexia nervosa and bulimia nervosa. Favaro, A., Tenconi, E., Santonastaso, P. Arch. Gen. Psychiatry (2006) [Pubmed]
  7. Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): I--A review of clinical, radiologic and genetic aspects. Bornebroek, M., Haan, J., Maat-Schieman, M.L., Van Duinen, S.G., Roos, R.A. Brain Pathol. (1996) [Pubmed]
  8. Anger attacks in unipolar depression, Part 1: Clinical correlates and response to fluoxetine treatment. Fava, M., Rosenbaum, J.F., Pava, J.A., McCarthy, M.K., Steingard, R.J., Bouffides, E. The American journal of psychiatry. (1993) [Pubmed]
  9. Revising and assessing axis II, Part II: toward an empirically based and clinically useful classification of personality disorders. Westen, D., Shedler, J. The American journal of psychiatry. (1999) [Pubmed]
  10. Mood, major depression, and fluoxetine response in cigarette smokers. Dalack, G.W., Glassman, A.H., Rivelli, S., Covey, L., Stetner, F. The American journal of psychiatry. (1995) [Pubmed]
  11. The impact of early specialization on the clinical competence of residents. Gonnella, J.S., Veloski, J.J. N. Engl. J. Med. (1982) [Pubmed]
  12. Population biology of infectious diseases: Part II. May, R.M., Anderson, R.M. Nature (1979) [Pubmed]
  13. Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation. Schrem, H., Klempnauer, J., Borlak, J. Pharmacol. Rev. (2004) [Pubmed]
  14. Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Schrem, H., Klempnauer, J., Borlak, J. Pharmacol. Rev. (2002) [Pubmed]
  15. The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages. Unanue, E.R. Adv. Immunol. (1981) [Pubmed]
  16. Do urinary estrogen metabolites reflect the differences in breast cancer risk between Singapore Chinese and United States African-American and white women? Ursin, G., Wilson, M., Henderson, B.E., Kolonel, L.N., Monroe, K., Lee, H.P., Seow, A., Yu, M.C., Stanczyk, F.Z., Gentzschein, E. Cancer Res. (2001) [Pubmed]
  17. Steroids in the treatment of clinical septic shock. Schumer, W. Ann. Surg. (1976) [Pubmed]
  18. Persantine-Aspirin Reinfarction Study. Part II. Secondary coronary prevention with persantine and aspirin. Klimt, C.R., Knatterud, G.L., Stamler, J., Meier, P. J. Am. Coll. Cardiol. (1986) [Pubmed]
  19. Cerebral atherosclerosis in Japanese. Part 5: relationship between cholesterol deposition and glycosaminoglycans. Nakamura, M., Imaizumi, K., Shigemi, U., Nakashima, Y., Kikuchi, Y. Stroke (1976) [Pubmed]
  20. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Castegna, A., Aksenov, M., Aksenova, M., Thongboonkerd, V., Klein, J.B., Pierce, W.M., Booze, R., Markesbery, W.R., Butterfield, D.A. Free Radic. Biol. Med. (2002) [Pubmed]
  21. The use of Part I National Board scores in the selection of residents in ophthalmology and otolaryngology. McCollister, R.J. JAMA (1988) [Pubmed]
  22. Intestinal and hepatic complications of human bone marrow transplantation. Part I. McDonald, G.B., Shulman, H.M., Sullivan, K.M., Spencer, G.D. Gastroenterology (1986) [Pubmed]
  23. Charge movement in skeletal muscle fibers paralyzed by the calcium-entry blocker D600. Hui, C.S., Milton, R.L., Eisenberg, R.S. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  24. Human autonomy and the frontal lobes. Part I: Imitation and utilization behavior: a neuropsychological study of 75 patients. Lhermitte, F., Pillon, B., Serdaru, M. Ann. Neurol. (1986) [Pubmed]
  25. Mature eosinophils stimulated to develop in human cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. Part I. Piecemeal degranulation of specific granules and distribution of Charcot-Leyden crystal protein. Dvorak, A.M., Furitsu, T., Letourneau, L., Ishizaka, T., Ackerman, S.J. Am. J. Pathol. (1991) [Pubmed]
  26. Areas 3a, 3b, and 1 of human primary somatosensory cortex. Part 2. Spatial normalization to standard anatomical space. Geyer, S., Schormann, T., Mohlberg, H., Zilles, K. Neuroimage (2000) [Pubmed]
  27. From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part I. Clarke, A.R., Atkinson, T., Holbrook, J.J. Trends Biochem. Sci. (1989) [Pubmed]
  28. From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part II. Clarke, A.R., Atkinson, T., Holbrook, J.J. Trends Biochem. Sci. (1989) [Pubmed]
  29. Cholesterol screening in asymptomatic adults, revisited. Part 2. Garber, A.M., Browner, W.S., Hulley, S.B. Ann. Intern. Med. (1996) [Pubmed]
  30. Myocardial preconditioning. Part of the adenosine revival. Mullane, K. Circulation (1992) [Pubmed]
  31. Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo. Livelli, F.D., Johnson, R.A., McEnany, M.T., Sherman, E., Newell, J., Block, P.C., DeSanctis, R.W. Circulation (1978) [Pubmed]
  32. Characterization of the histamine H4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives. Smits, R.A., Lim, H.D., Stegink, B., Bakker, R.A., de Esch, I.J., Leurs, R. J. Med. Chem. (2006) [Pubmed]
  33. Alteplase versus urokinase for occluded hemodialysis catheters. Zacharias, J.M., Weatherston, C.P., Spewak, C.R., Vercaigne, L.M. The Annals of pharmacotherapy. (2003) [Pubmed]
  34. Disturbed copper transport in humans. Part 1: mutations of the ATP7A gene lead to Menkes disease and occipital horn syndrome. Seidel, J., Møller, L.B., Mentzel, H.J., Kauf, E., Vogt, S., Patzer, S., Wollina, U., Zintl, F., Horn, N. Cell. Mol. Biol. (Noisy-le-grand) (2001) [Pubmed]
  35. Genetics of childhood disorders: XVII. ADHD, Part 1: The executive functions and ADHD. Barkley, R.A. Journal of the American Academy of Child and Adolescent Psychiatry. (2000) [Pubmed]
  36. Receptor-mediated tumor targeting with radiopeptides. Part 1. General concepts and methods: applications to somatostatin receptor-expressing tumors. Eberle, A.N., Mild, G., Froidevaux, S. J. Recept. Signal Transduct. Res. (2004) [Pubmed]
  37. Adhesion of fibronectin, vitronectin, laminin, and collagen type IV to intraocular lens materials in pseudophakic human autopsy eyes. Part 1: histological sections. Linnola, R.J., Werner, L., Pandey, S.K., Escobar-Gomez, M., Znoiko, S.L., Apple, D.J. Journal of cataract and refractive surgery. (2000) [Pubmed]
  38. The generalist role of specialty physicians: is there a hidden system of primary care? Rosenblatt, R.A., Hart, L.G., Baldwin, L.M., Chan, L., Schneeweiss, R. JAMA (1998) [Pubmed]
  39. The association between local diagnostic testing intensity and invasive cardiac procedures. Wennberg, D.E., Kellett, M.A., Dickens, J.D., Malenka, D.J., Keilson, L.M., Keller, R.B. JAMA (1996) [Pubmed]
  40. Searching for inaccuracy in clinical laboratory testing using Medicare data. Evidence for prothrombin time. Mennemeyer, S.T., Winkelman, J.W. JAMA (1993) [Pubmed]
  41. An experiment in medical education. A critical analysis using traditional criteria. Goodman, L.J., Brueschke, E.E., Bone, R.C., Rose, W.H., Williams, E.J., Paul, H.A. JAMA (1991) [Pubmed]
  42. Does practice make perfect when interpreting mammography? Part II. Elmore, J.G., Miglioretti, D.L., Carney, P.A. J. Natl. Cancer Inst. (2003) [Pubmed]
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