Disease relevance of PART1

• This study identified a novel gene that we have designated PART-1 (prostate androgen-regulated transcript 1), which exhibited increased expression upon exposure to androgens in the LNCaP prostate cancer cell line [1].
• Ovarian cancer, Part II [2].
• Brain tumor. Part 2 [3].
• Herpesvirus infections of pregnancy. Part II: Herpes simplex virus and varicella-zoster virus infections [4].
• Herpesvirus infections of pregnancy. Part I: Cytomegalovirus and Epstein-Barr virus infections [5].

Psychiatry related information on PART1

• SETTINGS AND PARTICIPANTS: Part of the sample of subjects with eating disorders and all of the controls took part in a prevalence study carried out in 2 randomly selected areas of Padua [6].
• The characteristic pathological abnormalities and its implications for Alzheimer's disease will be discussed in Part II of this article [7].
• Anger attacks in unipolar depression, Part 1: Clinical correlates and response to fluoxetine treatment [8].
• Revising and assessing axis II, Part II: toward an empirically based and clinically useful classification of personality disorders [9].
• METHOD: Part I: Three hundred sixty-eight smokers who enrolled in a smoking cessation treatment study completed baseline self-rating scales [10].

High impact information on PART1

• The results show that physicians in family medicine, internal medicine, or flexible programs score higher on Part III than do those in surgery, pediatrics, obstetrics/gynecology, psychiatry, or pathology, even after correction for their performance on Part II of the boards [11].
• Population biology of infectious diseases: Part II [12].
• Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation [13].
• Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression [14].
• The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages [15].

Chemical compound and disease context of PART1

• Breast cancer risk is substantially lower in Singapore than in women from the United STATES: Part of the risk discrepancy is probably explained by differences in the production of endogenous estrogens, but differences in the pathway by which estrogen is metabolized may also play a role [16].
• In Part I, 172 consecutive patients in septic shock admitted over an 8-year period were treated with either steroid or saline: 43 received dexamethasone (DMP), 43 received methylprednisolone (MPS), and 86 received saline [17].
• In the Persantine-Aspirin Reinfarction Study, Part II (PARIS II), 3,128 persons who had recovered from myocardial infarction, suffered from 4 weeks to 4 months previously, were randomized into two groups: dipyridamole (Persantine) plus aspirin (n = 1,563) and placebo (n = 1,565) [18].
• Cerebral atherosclerosis in Japanese. Part 5: relationship between cholesterol deposition and glycosaminoglycans [19].
• Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1 [20].

Biological context of PART1

• PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12 [1].
• Cloning and analysis of the putative PART-1 promoter region identified a potential binding site for the homeobox gene PBX-la, but no consensus androgen response element or sterol-regulatory element binding sites were identified [1].
• We used a radiation hybrid panel and fluorescence in situ hybridization to map the PART-1 gene to chromosome 5q12, a region that has been suggested to harbor a prostate tumor suppressor gene [1].
• Northern analysis demonstrated that PART-1 is highly expressed in the prostate gland relative to other normal human tissues and is expressed as different transcripts using at least three different polyadenylation signals [1].
• The use of Part I National Board scores in the selection of residents in ophthalmology and otolaryngology [21].

Anatomical context of PART1

• Intestinal and hepatic complications of human bone marrow transplantation. Part I [22].
• We report measurements of nonlinear charge movement in frog skeletal muscle fibers paralyzed by the calcium-entry blocker [Schwartz, A. & Taira, N., eds. (1983) Circ. Res. 52, Part II, Number 2, 1-181.] D600 (methoxyverapamil, recently renamed gallopamil) [23].
• Human autonomy and the frontal lobes. Part I: Imitation and utilization behavior: a neuropsychological study of 75 patients [24].
• Mature eosinophils stimulated to develop in human cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. Part I. Piecemeal degranulation of specific granules and distribution of Charcot-Leyden crystal protein [25].
• Areas 3a, 3b, and 1 of human primary somatosensory cortex. Part 2. Spatial normalization to standard anatomical space [26].

Associations of PART1 with chemical compounds

• In Part I of this article, the naturally evolved protein framework of lactate dehydrogenase is investigated by genetically introduced modifications which reveal the structural basis of its catalytic and substrate-binding properties [27].
• In Part II, the conclusions are used in the design and synthesis of two modified forms of the enzyme; one in which the substrate specificity is shifted to produce a more effective malate dehydrogenase than that isolated from the host organism and one which no longer requires its allosteric activator (fructose 1,6-bisphosphate) [28].
• Cholesterol screening in asymptomatic adults, revisited. Part 2 [29].
• Myocardial preconditioning. Part of the adenosine revival [30].
• In Part II, 67 patients with unexplained postoperative fever were given indomethacin (100 mg per day) or placebo for 7 days by a randomized, double-blind protocol [31].

Physical interactions of PART1

• Characterization of the histamine H4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives [32].

Other interactions of PART1

• METHODS: Part 1 of the study prospectively investigated the effect of alteplase in reestablishing adequate blood flow through partially or completely occluded vascular catheters in 30 hemodialysis patients [33].
• Disturbed copper transport in humans. Part 1: mutations of the ATP7A gene lead to Menkes disease and occipital horn syndrome [34].
• Genetics of childhood disorders: XVII. ADHD, Part 1: The executive functions and ADHD [35].
• Receptor-mediated tumor targeting with radiopeptides. Part 1. General concepts and methods: applications to somatostatin receptor-expressing tumors [36].
• Adhesion of fibronectin, vitronectin, laminin, and collagen type IV to intraocular lens materials in pseudophakic human autopsy eyes. Part 1: histological sections [37].

Analytical, diagnostic and therapeutic context of PART1

• DESIGN: A cross-sectional study of all ambulatory care recorded in Part B of the Washington State Medicare Claims Database in 1994 and 1995 [38].
• DESIGN: A population-based cohort study using Medicare Part B data (physician services) [39].
• DESIGN--Retrospective analysis of Medicare Part B outpatient claims, Part A hospitalization bills, and death records using a case-control study [40].
• As part of an evaluation of this new curriculum, students in the two curricula were compared using three traditional measurements: (1) test scores from the National Board of Medical Examiners, Part I; (2) test scores from the National Board of Medical Examiners, Part II; and (3) performance on an oral examination [41].
• Does practice make perfect when interpreting mammography? Part II [42].

References