Disease relevance of Laminectomy

• We present seven patients with multilevel cervical spondylotic myelopathy and superimposed midline soft disc herniation who were treated by decompressive laminectomies of the spondylotic segments followed by transdural excision of the anteriorly located disc extrusion [1].
• Outcome after laminectomy for lumbar spinal stenosis. Part I: Clinical correlations [2].
• INTERVENTION: The patient was treated with a laminectomy at the level of stenosis accompanied by posterior instrumentation and fusion from C5 to T3 [3].
• This is a report of a double-bind controlled trial to test the hypothesis that peroperative local infiltration of the wound of lumbar laminectomy with bupivacaine produces a significant reduction in postoperative back pain [4].
• We report a case of anaphylaxis caused by irrigation with a bacitracin solution during lumbar laminectomy [5].

Psychiatry related information on Laminectomy

• Twenty-five postoperative lumbar laminectomy and diskectomy patients were administered the MMPI and evaluated by physical examination which included the Burns' Bench Test. In this test the patient is asked to kneel on a bench with knees and hips flexed and place his fingers on the floor [6].

High impact information on Laminectomy

• Free fatty acid (FFA), diacylglycerol (acyl2Gro), icosanoid, phospholipid, and cholesterol levels were measured in samples of cat spinal cord (L2) that were frozen in situ with vertebrae intact, at various times after laminectomy, and at various times after laminectomy with compression trauma to the spinal cord [7].
• Three- to 7-week-old postnatal and adult (>10-week-old) rats were anesthetized and laminectomy was performed between C5 and Th1 to expose the dorsal surface of the cervical spinal cord [8].
• The region of the dorsal surface of C2 spinal cord was exposed by a laminectomy and an electrode placed for recording evoked activity from sinus stimulation and spontaneous activity of the same cells [9].
• The p9 and p11 positivities fused after laminectomy, suggesting that conductance change at the root entry to the bony spinal canal separates these components in the noncephalic reference recording [10].
• One patient received high-dose dexamethasone after laminectomy for diagnostic biopsy; otherwise, dexamethasone was used only as an anti-emetic prior to chemotherapy [11].

Chemical compound and disease context of Laminectomy

• METHODS: Patients who had undergone previous laminectomy and who had MR imaging evidence of recurrent herniated disk were enrolled in the study and underwent lumbar MR imaging with the nonionic medium gadodiamide and on a subsequent day with the ionic contrast medium gadopentetate dimeglumine [12].
• It also facilitates laminectomy of C1 in patients with associated myelopathy [13].
• The girl underwent laminectomy of C2 with total removal of the exostosis [14].
• Two years after radiation therapy for his Hodgkin's lymphoma, the first patient underwent a C6 laminectomy at an outside institution for resection of a benign neurofibroma [15].
• Postoperative highcervical quadriplegia after transoral biopsy of a paravertebral tuberculous abscess with epidural extension: complete resolution after decompressive laminectomy and high-dose methylprednisolone [16].

Biological context of Laminectomy

• Evans blue albumin leakage and cauda equina adhesion started to appear in nearly a same phase after laminectomy, followed by a plateau of vascular permeability facilitating complete cauda equina adhesion by 24 hours after surgery [17].
• With the posterior approach, postoperative ROM (range of motion) could be better maintained, and horizontal displacement was improved in more cases by laminoplasty compared with laminectomy [18].

Anatomical context of Laminectomy

• Foramen magnum decompression and C1 laminectomy were performed, and the dura was exposed [19].
• A laminectomy was not performed unless the cerebellar tonsils were herniated below C1 [20].
• CONCLUSIONS: The authors conclude that decompressive laminectomy in which the facet joints are preserved can be performed in the rheumatoid arthritis-affected cervical spine in selected patients in whom signs of cord compression are demonstrated, but in whom radiographic and preoperative signs of instability are not [21].
• The indication for fusion was instability of the occiput-C1-C2 complex as a result of Chiari malformation, rheumatoid disease, skull base tumor resection, basilar invagination, ankylosing spondylitis, Down's syndrome, cervical laminectomy, and trauma [22].
• Five monkeys received six intercostal nerve autografts and fibrin glue containing acidic fibroblast growth factor (2.1 microg/ml) whereas controls underwent the identical laminectomy procedure but did not receive the nerve grafts [23].

Associations of Laminectomy with chemical compounds

• Laminectomy for decompression and diagnosis, administration of antischistosomal medications, and high-dose oral prednisone early in the illness are recommended [24].
• Uninjured surgical (laminectomy) control animals showed modest but significant declines in aspartate and glutamate levels, but not in other amino acids, at all time points [25].
• Twenty-two patients who had undergone at least one prior laminectomy, who were still symptomatic, were randomized to receive 50 mg of lidocaine epidurally with: (a) 75 mg triamcinolone diacetate (TR); or (b) 8 mg of preservative-free morphine (MP); or (c) both (TR and MP), at 1 month intervals for 3 consecutive months [26].
• Bone scans using Tc-99m diphosphonate were found to become abnormal within 2 weeks after laminectomy in less than half of patients regardless of the extent of the operation [27].
• In a second series of experiments the effect of SCS, applied acutely via a laminectomy, on the early component (latency: 8-12 msec) of the flexor reflex was studied [28].

Gene context of Laminectomy

• The procedure involved laminectomies at T11, T12, and L1, followed by a midline myelotomy [29].
• She underwent a laminectomy at T10-T11, and no further neurological deterioration was seen immediately after surgery [30].
• Mobility of the cervical spine was reduced considerably after laminectomy, both in CS and OPLL cases [31].
• However, controls undergoing only a C2 laminectomy do not demonstrate alterations in GFAP IR compared to non-operated controls [32].
• In contrast, the expression of myelin basic protein was decreased in the lesion compared with controls that received laminectomy only [33].

Analytical, diagnostic and therapeutic context of Laminectomy

• A midline craniotomy and C2 laminectomy were performed for access to the superior sagittal sinus and C2 dorsal horn, respectively [34].
• Fifty-seven (approximately 28%) patients were investigated by metrizamide myelography, computerized tomography (CT), magnetic resonance imaging (MRI), laminectomy, or neurohistopathology [35].
• ODC activity was significantly increased 4 h after laminectomy in L4 and in adjacent L3 and L5 segments and compression to L4 produced a further increase 4 h after injury as compared with the intact control group [36].
• Rabbits were anesthetized with halothane and after arterial and venous cannulation, an intrathecal catheter was placed via a lumbar laminectomy [37].
• Under general anesthesia, patients received high thoracic midline dorsal column myelotomies after T1 or T2 laminectomy [38].

References