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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Biotransformation of alpha- and beta-ionones by immobilized cells of Nicotiana tabacum.

Immobilized cells of Nicotiana tabacum reduced the carbon-carbon double bond adjacent to the carbonyl group and then the carbonyl group itself of the dienone compounds, alpha-ionone and beta-ionone. In addition, the selectivity for the reduction of the double bond adjacent to the carbonyl group could be enhanced by performing the biotransformation in medium with a pH near the optimal pH of the enone reductase which specifically catalyses the reduction of the alpha, beta-unsaturated double bond of s-trans-enones.[1]

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