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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy.

We examined the inferior olivary nucleus from four cases of olivary hypertrophy and six control cases immunohistochemically with an anti-synaptophysin ( SYP) antibody. Our study revealed the altered SYP-immunoreactive pattern in the hypertrophied olives, consisting of an increased number of SYP-immunoreactive dots on neuronal cell bodies in spite of its decreased immunoreactivity in the neuropil. Because SYP is a marker protein for presynaptic vesicles, presynaptic terminals in the inferior olivary nucleus seem to change their distribution during the course of olivary hypertrophy.[1]

References

  1. Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy. Kawanami, T., Kato, T., Llena, J.F., Hirano, A., Sasaki, H. Neurosci. Lett. (1994) [Pubmed]
 
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