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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Nucleotide sequence of the Salmonella typhimurium trpR gene.

The sequence of the Salmonella typhimurium trpR gene and flanking DNA was determined on both strands. The DNA sequence predicts a polypeptide product of 108 amino acids with a molecular weight of 12,274 daltons. The TrpR protein of S. typhimurium differs by three amino acid residues from that of E. coli. The promoter/operator region of trpR is completely conserved between E. coli and S. typhimurium. The nucleotide sequence of the trpR sector of the S. typhimurium genome was 87.4% identical to the corresponding region of the E. coli genome. Within the protein coding segments of the two organisms, 94.4% of the amino acid residues were identical. In S. typhimurium, as in E. coli, there is a Palindromic Unit element (PU) between the translation termination triplet of trpR and that of a divergently oriented unidentified reading frame (URF-143). However, the PU segment of S. typhimurium is 85 nucleotides shorter than its E. coli counterpart.[1]


  1. Nucleotide sequence of the Salmonella typhimurium trpR gene. Skrypka, I., Somerville, R.L. DNA Seq. (1994) [Pubmed]
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