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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Oncogenic and tumor-promoting Spermatophytes and Pteridophytes and their active principles.

A survey and discussion are presented of plants classified as Spermatophyta and Pteridophyta, extracts of which have been shown to be oncogenic or tumor-promoting in animals. The active oncogenic and tumor-promoting principles, where known, have been identified. They represent tannins; pyrrolizidine, indole, tropolone, quinoline, purine, and benzophenanthridine alkaloids; nitroso compounds; triterpene glycosides; lignans; isoflavans; allyl benzenoids; simple (nu-pyrenes; and carbocyclic hydroxy acids. A total of 28 compounds of known structure have been identified as oncogens and several phorbol esters as tumor-promoters. Plants known to contain any of the 28 oncogens (excluding shikimic acid and caffeine) have been tabulated; they represent at least 454 species, 110 genera, and 34 families of Spermatophyta and Pteridophyta.[1]

References

  1. Oncogenic and tumor-promoting Spermatophytes and Pteridophytes and their active principles. Farnsworth, N.R., Bingel, A.S., Fong, H.H., Saleh, A.A., Christenson, G.M., Saufferer, S.M. Cancer treatment reports. (1976) [Pubmed]
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