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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Dural ectasia of the optic nerve sheath in neurofibromatosis type 1: CT and MR features.

OBJECTIVE: Optic nerve glioma is a common finding in patients with neurofibromatosis type 1 (NF-1). Although dural ectasia of the optic nerve is encountered rarely, it has to be considered in the differential diagnosis. MATERIALS AND METHODS: Three patients affected by NF-1 were examined sequentially by CT and MRI. RESULTS: Computed tomography demonstrated nonprogressing enlargement of the anterior optic pathways. Magnetic resonance imaging displayed widening of the perioptic dural sheath without any suggestion of tumor. CONCLUSION: These findings are compatible with meningocele or dural ectasia of the optic nerve sheath. This entity represents a differential diagnosis to optic glioma in patients with NF-1.[1]


  1. Dural ectasia of the optic nerve sheath in neurofibromatosis type 1: CT and MR features. Lövblad, K.O., Remonda, L., Ozdoba, C., Huber, P., Schroth, G. Journal of computer assisted tomography. (1994) [Pubmed]
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