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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Meningocele


High impact information on Meningocele


Chemical compound and disease context of Meningocele


Anatomical context of Meningocele


Gene context of Meningocele

  • FISH analysis demonstrated haploinsufficiency of HLXB9, a gene identified in the triad of a presacral mass (teratoma or anterior meningocele), sacral agenesis, and anorectal malformation, which constitutes the Currarino syndrome [18].
  • In conclusion, reconstruction of the superolateral wall and repair of a meningocele in a patient with NF1 is worthwhile and can be followed by excellent cosmetic results [19].
  • Two had extensive vertebral fusion and 18 were united in the dorsal midline, all with a meningocele, vertebral anomaly, and/or bony or neural connection [20].
  • Two siblings are described with clinical features of Joubert syndrome associated with unilateral ptosis, severe visual disturbances with normal appearing fundi, and an occipital meningocele; one child also had polydactyly [21].


  1. Partial trisomy 8q in half-sisters with distinct dysmorphic patterns not similar to the trisomy 8 mosaicism syndrome. Schinzel, A. Hum. Genet. (1977) [Pubmed]
  2. Currarino triad with dual pathology in the presacral mass: report of a case. Thambidorai, C.R., Muin, I., Razman, J., Zulfiqar, A. Dis. Colon Rectum (2003) [Pubmed]
  3. An unusual pterygopalatine meningocele associated with neurofibromatosis type 1. Case report. Chapman, P.H., Curtin, H.D., Cunningham, M.J. J. Neurosurg. (2000) [Pubmed]
  4. Neonatal diagnosis of a presacral mass in the presence of congenital anal stenosis and partial sacral agenesis. Brem, H., Beaver, B.L., Colombani, P.M., Zinreich, J., Scherer, L.R., Carson, B.S., Haller, J.A. J. Pediatr. Surg. (1989) [Pubmed]
  5. Closed spinal dysraphism: analysis of clinical, radiological, and surgical findings in 104 consecutive patients. Scatliff, J.H., Kendall, B.E., Kingsley, D.P., Britton, J., Grant, D.N., Hayward, R.D. AJR. American journal of roentgenology. (1989) [Pubmed]
  6. Triamcinolone acetonide-induced meningocele and meningoencephalocele in rhesus monkeys. Hendrickx, A.G., Tarara, R.P. Am. J. Pathol. (1990) [Pubmed]
  7. Sequestrated meningoceles of scalp: extracranial meningeal heterotopia. Bale, P.M., Hughes, L., de Silva, M. Hum. Pathol. (1990) [Pubmed]
  8. Terminal myelocystoceles: a series of 17 cases. Gupta, D.K., Mahapatra, A.K. J. Neurosurg. (2005) [Pubmed]
  9. Linkage analysis of a candidate locus (HLA) in autosomal dominant sacral defect with anterior meningocele. Chatkupt, S., Speer, M.C., Ding, Y., Thomas, M., Stenroos, E.S., Dermody, J.J., Koenigsberger, M.R., Ott, J., Johnson, W.G. Am. J. Med. Genet. (1994) [Pubmed]
  10. Occipital meningoceles in patients with the Dandy-Walker syndrome. Bindal, A.K., Storrs, B.B., McLone, D.G. Neurosurgery (1991) [Pubmed]
  11. Anterior sacral meningocele and the scimitar sign. Report of a case. Kovalcik, P.J., Burke, J.B. Dis. Colon Rectum (1988) [Pubmed]
  12. CSF rhinorrhea from a transclival meningocele demonstrated with metrizamide CT cisternography. Case report. Lockwood, A.H., Quencer, R.M., Page, L.K. J. Neurosurg. (1980) [Pubmed]
  13. Prevention of etretinate-induced craniofacial malformations by vitamin B6 in the rat. Jacobsson, C., Granström, G. Eur. J. Oral Sci. (1996) [Pubmed]
  14. Valproic acid-induced spina bifida: a mouse model. Ehlers, K., Stürje, H., Merker, H.J., Nau, H. Teratology (1992) [Pubmed]
  15. Experimentally induced cranial meningocele and cerebral microgyria. Sato, H., Sato, N., Tamaki, N., Matsumoto, S. Brain Dev. (1982) [Pubmed]
  16. Dandy-Walker syndrome: analysis of 21 cases. Tal, Y., Freigang, B., Dunn, H.G., Durity, F.A., Moyes, P.D. Developmental medicine and child neurology. (1980) [Pubmed]
  17. Anterior cervicothoracic meningocele treated by cystopleural shunt. Case report and review of the literature. Tander, B., KiLincoglu, B.F., Ziyal, I., Dinçbal, M.N., Aydin, Y. Journal of neurosurgical sciences. (2004) [Pubmed]
  18. Prenatal diagnosis of sacrococcygeal teratoma with constitutional partial monosomy 7q/trisomy 2p. Le Caignec, C., Winer, N., Boceno, M., Delnatte, C., Podevin, G., Liet, J.M., Quere, M.P., Joubert, M., Rival, J.M. Prenat. Diagn. (2003) [Pubmed]
  19. Successful surgical repair of progressive exophthalmos caused by a meningocele in a patient with neurofibromatosis Type 1. Case report. de Vries, J., Freihofer, H.P., Menovsky, T., Cruysberg, J.R. J. Neurosurg. (1998) [Pubmed]
  20. Rachipagus conjoined twins: they really do occur! Spencer, R. Teratology (1995) [Pubmed]
  21. Joubert syndrome associated with unilateral ptosis and Leber congenital amaurosis. Houdou, S., Ohno, K., Takashima, S., Takeshita, K. Pediatric neurology. (1986) [Pubmed]
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