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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Congenital diaphragmatic hernia in the Brachmann-de Lange syndrome.

We present 12 children with typical Brachmann-de Lange syndrome and congenital diaphragmatic hernia. Affected children were more likely to be of low birth weight and to have major upper limb malformations. Hernia repair was attempted in 4 of these children, and only one survived past 12 months. Newborn infants with congenital diaphragmatic hernia should be examined carefully for evidence of the Brachmann-de Lange syndrome because diagnosis of this condition may influence their clinical management and prognosis.[1]


  1. Congenital diaphragmatic hernia in the Brachmann-de Lange syndrome. Cunniff, C., Curry, C.J., Carey, J.C., Graham, J.M., Williams, C.A., Stengel-Rutkowski, S., Lüttgen, S., Meinecke, P. Am. J. Med. Genet. (1993) [Pubmed]
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