Disease relevance of Infant, Low Birth Weight

• MAIN OUTCOME MEASURES--We contrasted mean birth weight and rates of low birth weight (< 2500 g) among cocaine users with one to three prenatal care visits, four or more visits, and unknown numbers of visits with users who reported no prenatal care [1].
• The background for this study comes from findings suggesting a correlation between low birth weight and the development of NIDDM and high blood pressure [2].
• Birth weight and the insulin resistance syndrome: association of low birth weight with truncal obesity and raised plasminogen activator inhibitor-1 but not with abdominal obesity or plasma lipid disturbances [3].
• L-cysteine in metabolic acidosis of low-birth-weight infants [4].
• The patient came from an inbred Mennonite family, and though the mutation identified her as an AME patient, she had a normal birth weight and did not demonstrate the typical features of AME, such as hypokalemic alkalosis, low birth weight, failure to thrive, poor growth, and in many cases nephrocalcinosis [5].

Psychiatry related information on Infant, Low Birth Weight

• Obstetric determinants of neonatal survival: influence of willingness to perform cesarean delivery on survival of extremely low-birth-weight infants. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units [6].

High impact information on Infant, Low Birth Weight

• Infants with very low birth weights have less need of transfusions if given epoetin beta during the first six weeks of life (250 IU per kilogram three times a week) [7].
• Immunization levels among premature and low-birth-weight infants and risk factors for delayed up-to-date immunization status. Centers for Disease Control and Prevention Vaccine Safety Datalink Group [8].
• CONCLUSION.--This meta-analysis suggests that low-dose aspirin reduces the risks of PIH and severe low birth weight, with no observed risk of maternal or neonatal adverse effects [9].
• Vasculopathic hepatotoxicity associated with E-Ferol syndrome in low-birth-weight infants [10].
• Early administration of vitamin E, while not affecting the frequency of RLF, will significantly reduce its severity and subsequent eye damage, and such treatment is recommended for all low-birth-weight infants of less than 1250 g who require supplementary oxygen [11].

Chemical compound and disease context of Infant, Low Birth Weight

• Renal functions of low birth weight infants with hyperglycemia and glucosuria produced by glucose infusions [12].
• Insulin infusion with parenteral nutrition in extremely low birth weight infants with hyperglycemia [13].
• Indomethacin for prevention of intraventricular hemorrhage in low birth weight infants [14].
• Digoxin therapy in low-birth-weight infants with patent ductus arteriosus [15].
• Studies of glutamine supplementation in low birth weight infants and critically ill adults suggest benefits, especially in terms of decreased nosocomial infections [16].

Biological context of Infant, Low Birth Weight

• Short stature and low birth weight are both associated with increased risk of developing diabetic nephropathy, supporting the hypothesis that genetic predisposition or factors operating in utero, in early childhood, or both contribute to the development of diabetic nephropathy [17].
• At 36 weeks gestation, GHBP was significantly elevated (P < 0.01) in those women whose neonates had low birth weight (< 10th percentile) [18].
• Impaired glucose tolerance and elevated blood pressure in low birth weight, nonobese, young south african adults: early programming of cortisol axis [19].
• During pregnancy, low concentrations of dietary and circulating folate are associated with increased risks of preterm delivery, infant low birth weight, and fetal growth retardation [20].
• Women with a low mean daily folate intake (</-240 microgram/d) had an approximately twofold greater risk of preterm delivery and infant low birth weight after maternal characteristics, energy intake, and other correlated nutrients were controlled for [21].

Anatomical context of Infant, Low Birth Weight

• Thus, low birth weight in conjunction with rapid childhood gains in weight especially as subcutaneous fat, produces poor glucose tolerance in 7-year-old children and can make them susceptible to the development of Type II diabetes later in life [22].
• The fatty acid composition of plasma phospholipids, red blood cell (RBC) phosphatidylcholine (PC), and phosphatidylethanolamine (PE) was determined for low-birth-weight (LBW) infants when full oral feeding commenced (day 0) and after a further 28 d (day 28) [23].
• Erythrocyte and plasma cholesterol ester long-chain polyunsaturated fatty acids of low-birth-weight babies fed preterm formula with and without ribonucleotides: comparison with human milk [24].
• Plasma apolipoprotein A-I and B concentrations in growth-retarded fetuses: a link between low birth weight and adult atherosclerosis [25].
• Their common features were mental and growth retardation, low birth weight, microcephaly, stubby nose, hypertelorism, strabismus, wide set nipples, single transverse palmar creases, undescended testes, and hypoplastic scrotum [26].

Associations of Infant, Low Birth Weight with chemical compounds

• Parenteral nutrition in low-birth-weight infants [27].
• The highest levels of IRS variables and total and LDL cholesterol were in children of low birth weight but high fat mass at 8 years [28].
• Disproportionate shape at birth was associated with reduced hepatic gluconeogenic enzyme concentrations and low birth weight pigs had reduced basal glucose concentrations at 12 months of age [29].
• Patterns of glycine and taurine conjugation of bile acids in duodenal juice have been studied in 20 low birth weight babies at 12 and 22 days of age [30].
• The highest insulin concentrations were found in children with a low birth weight and a low gamma-linolenic acid concentration at birth [31].

Gene context of Infant, Low Birth Weight

• Among primigravidas, placental TNF-alpha concentrations were significantly higher in the presence of severe maternal anemia, and both IFN-gamma and TNF-alpha were significantly elevated when a low birth weight, rather than normal weight, infant was delivered [32].
• OBJECTIVE: We aimed to determine whether a common, recently discovered deletion polymorphism in the DHFR gene is a risk factor for preterm delivery or low birth weight [33].
• Prevalence of genetic prothrombotic markers (FVL, MTHFR, FIIG20210A) and levels of plasma homocysteine were assayed in 166 premature (mean gestational age: 30.9+/-2.3 weeks) and low birth weight (mean weight: 1327+/-319 grams) infants [34].
• This paper focuses on recent evidence, which suggest that low levels of placental 11 beta-HSD2 result in increased exposure of the fetus to maternal glucocorticoid and low birth weight [35].
• In MRX12, prematurity or low birth weight, hypotelorism and short stature were seen in several affected males [36].

Analytical, diagnostic and therapeutic context of Infant, Low Birth Weight

• In a population-based case-control study, we assessed the relation between cocaine use and the risk of low birth weight in Alameda County, California, excluding women who used heroin and/or methadone during pregnancy [37].
• Longitudinal study of free thyroxine in low-birth-weight infants by paper disk method [38].
• We investigated the abilities of the OptiMAL rapid immunochromatographic strip test for P. falciparum lactate dehydrogenase and species-specific PCR performed on peripheral blood to detect placental infection or malaria-associated low birth weight [39].
• Serum vitamin K1 concentrations after oral administration of vitamin K1 in low birth weight infants [40].
• We conclude that maintenance indomethacin therapy, in comparison with short-term indomethacin therapy, decreases the incidence of surgical PDA ligations, eliminates most PDA recurrences, and does not increase toxic effects of indomethacin in the low birth weight infant with PDA [41].

References