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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The use of monoclonal antibodies to achieve immunological tolerance.

Monoclonal antibodies are potentially useful immunosuppressive agents. Short courses of CD4/CD8 monoclonal antibody can be used to guide the immune system of experimental animals to accept organ grafts and to arrest autoimmunity. This reprogramming is accompanied by potent T-cell dependent, 'infectious' regulatory mechanisms. A goal for therapeutic immunosuppression should be to understand and harness these innate immunoregulatory mechanisms.[1]

References

  1. The use of monoclonal antibodies to achieve immunological tolerance. Waldmann, H., Cobbold, S. Immunol. Today (1993) [Pubmed]
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