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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Ear disease is not a common complication in cystic fibrosis.

Although upper respiratory tract involvement is a common finding in cystic fibrosis ( CF), there is no agreement on whether hearing is affected in these patients. We studied 75 CF subjects and 50 healthy age-matched children with the same audiological protocol. An original scoring system was used to quantify the degree of hearing involvement (normal, mild, moderate and severe) in each subject. Prevalence of ear involvement in children with CF was similar to that in age-matched control subjects (25.4% and 18% respectively, P > 0.05). Ear disease in CF was not related to pulmonary disease, radiological sinusitis, nasal polyposis, or use of parenteral aminoglycosides. These data showed that the risk of ear disease in CF was not increased even if patients with severe audiological involvement were described only in the CF group.[1]


  1. Ear disease is not a common complication in cystic fibrosis. Cipolli, M., Canciani, M., Cavazzani, M., Uras, P., Zampieri, P., Mastella, G. Eur. J. Pediatr. (1993) [Pubmed]
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