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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Familial peripartum cardiomyopathy after molar pregnancy.

BACKGROUND: The potential complications of molar pregnancy are numerous and well defined, but associated peripartum cardiomyopathy has not been reported. CASE: A 16-year-old primigravida with a family history of peripartum cardiomyopathy requiring cardiac transplantation underwent suction curettage of a complete mole at 12 weeks' gestation. Three months after evacuation, she developed congestive heart failure. Radionuclide ventriculography demonstrated an ejection fraction of 30%, echocardiography revealed enlargement and ventricular hypokinesis, and a myocardial biopsy specimen contained hypertrophy and fibrosis without necrosis or active inflammation. The patient improved with medical therapy. CONCLUSION: Peripartum cardiomyopathy is a potential complication of molar pregnancy. In spite of the poor prognosis sometimes reported for this disease, good functional outcome may follow.[1]

References

  1. Familial peripartum cardiomyopathy after molar pregnancy. Massad, L.S., Reiss, C.K., Mutch, D.G., Haskel, E.J. Obstetrics and gynecology. (1993) [Pubmed]
 
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