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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Malignant melanocytic neural crest tumor in a young chicken (Gallus domesticus).

A malignant melanocytic tumor was found in an 8-week-old chicken. The tumor, which was composed of melanocytes, ganglion cells, nerves, and primitive pressure receptors, was examined by light microscopy, transmission electron microscopy, and immunohistochemistry. Antibodies to neuron-specific enolase ( NSE), glial fibrillary acidic protein (GFAP), and S-100 protein variably stained nerves, but melanocytes were only rarely immunolabelled by NSE antibodies and there was no specific staining of these cells for S-100 or GFAP. Ultrastructurally, neoplastic melanocytes contained melanin within melanosomes and premelanosomes and did not resemble Schwann cells.[1]

References

  1. Malignant melanocytic neural crest tumor in a young chicken (Gallus domesticus). Hafner, S., Latimer, K., Kelley, L.C., Wortham, K., Puette, M. Vet. Pathol. (1995) [Pubmed]
 
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