- The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines. Basu, H.S., Pellarin, M., Feuerstein, B.G., Marton, L.J. Anticancer Res. (1996)