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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Sequence analysis of the 5'-flanking region of the gene encoding human N-acetylglucosaminyltransferase III.

We have isolated and characterized the immediate (1651 bP) 5'-flanking region of the gene (GnT-III) encoding N-acetylglucosaminyltransferase III (GnT-III) from a human placental genomic library. Analysis of promoter elements shows a similarity to the 5'-flanking region of murine 1,4-galactosyltransferase. The sequence lacks obvious TATA elements and CCAAT boxes; however, putative regulatory sites, including 2 potential cAMP-response regulatory elements (CRE), 11 insulin-response element consensus sequences (IRE), 7 potential AP-2 binding sites, 2 SP1 consensus sequences (GC boxes) and 2 sequences similar to the half-palindromic glucocorticoid-responsive element (GRE), are present.[1]

References

  1. Sequence analysis of the 5'-flanking region of the gene encoding human N-acetylglucosaminyltransferase III. Kim, Y.J., Park, J.H., Kim, K.S., Chang, J.E., Ko, J.H., Kim, M.H., Chung, D.H., Chung, T.W., Choe, I.S., Lee, Y.C., Kim, C.H. Gene (1996) [Pubmed]
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