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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Growth hormone modulates IL-alpha and IFN-gamma release by murine splenocytes activated by LPS or porins of Salmonella typhimurium.

The effect of growth hormone ( GH) on the release of IL-1alpha and IFN-gamma from murine splenocytes was investigated. Their release from splenocytes activated by Salmonella enterica serovar Typhimurium lipopolysaccharide (LPS) 0.5 microg/ml was increased by c. 65% in the presence of GH 100 pg/ml. With splenocytes activated by S. Typhimurium porins 5 microg/ml, GH increased the production of both IL-1alpha and IFN-gamma by c. 56%. Polymyxin treatment abolished the cytokine-releasing activity of LPS but had no effect on the activity of the porin preparation.[1]

References

  1. Growth hormone modulates IL-alpha and IFN-gamma release by murine splenocytes activated by LPS or porins of Salmonella typhimurium. Sommese, L., Donnarumma, G., de l'Ero, C., Marcatili, A., Vitiello, M., Galdiero, M. J. Med. Microbiol. (1996) [Pubmed]
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