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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Quinazolinone derivatives: synthesis and binding evaluation on cholecystokinin receptors.

A series of 2-methyl-3-amino-4(H)-quinazolinone and of 2-phenyl-3-amino-4(H)-quinazolinone derivatives were synthesized and examined for their CCK receptor affinities. These compounds displayed micromolar affinities for CCK-B rather than CCK-A receptor and the obtained results confirm that the 4(3H)-quinazolinone nucleous represent a useful template for the development of selective CCK-B receptor ligands.[1]

References

  1. Quinazolinone derivatives: synthesis and binding evaluation on cholecystokinin receptors. Varnavas, A., Lassiani, L., Luxich, E., Zacchigna, M., Boccù, E. Farmaco (1996) [Pubmed]
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