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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Identification of a neuronal cell surface molecule, plexin, in mice.

We searched for mouse homologues of the cell adhesion protein plexin which was originally found in Xenopus, and obtained a cDNA encoding a plexin-like protein. We referred to this protein as mouse plexin 1. The overall amino acid identity between mouse plexin 1 and Xenopus plexin was 84%. As in the Xenopus plexin, the extracellular segment of mouse plexin 1 protein possessed three cysteine-rich domains which showed significant homology with the cysteine-rich domain of the c-Met proto-oncogene protein product (c-Met protein) and Met-like receptor protein tyrosine kinases. Northern blot analysis indicated that mouse plexin 1 was predominantly expressed in the brain.[1]

References

  1. Identification of a neuronal cell surface molecule, plexin, in mice. Kameyama, T., Murakami, Y., Suto, F., Kawakami, A., Takagi, S., Hirata, T., Fujisawa, H. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
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