The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effect of breast-tissue characteristics on the outcome of clinical breast examination training.

PURPOSE: To compare the effects of clinical breast examination (CBE) training on lump-detection rates in simulated premenopausal and postmenopausal breast tissue. METHOD: Two sets of six silicone models were made with background breast tissue simulating premenopausal tissue (most nodular, least soft) and postmenopausal breast tissue (least nodular, most soft) respectively. Eighteen lumps were located in each set of models. In September 1994, 82 housestaff and attending physicians with outpatient practices in the Division of General Internal Medicine at Northwestern University Medical School were randomized to a CBE-teaching intervention or a control group. Lump-detection rates for the two sets of models were measured before and after the teaching intervention. Analysis of covariance was used to analyze the effect of CBE training on examination sensitivity and specificity, controlling for baseline rates. RESULTS: CBE training increased lump-detection rates similarly and significantly in models simulating premenopausal and postmenopausal tissue, respectively. Specificity declined after training in models simulating postmenopausal tissue (p = 0.02) but was unchanged in models simulating premenopausal tissue (p = 0.54). CBE training had greater influence on sensitivity among house-staff than among attending physicians (p = 0.02). CONCLUSION: CBE training similarly affects lump detection in simulated premenopausal and postmenopausal breast tissue, but adversely affects specificity in simulated postmenopausal tissue only.[1]


  1. Effect of breast-tissue characteristics on the outcome of clinical breast examination training. McDermott, M.M., Dolan, N.C., Rademaker, A. Academic medicine : journal of the Association of American Medical Colleges. (1996) [Pubmed]
WikiGenes - Universities