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MeSH Review

Internship and Residency

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Disease relevance of Internship and Residency


Psychiatry related information on Internship and Residency


High impact information on Internship and Residency

  • We show that the murine GlcNAcT-IVa glycosyltransferase is required for Glut-2 residency on the beta cell surface by constructing a cell-type- and glycoprotein-specific N-glycan ligand for pancreatic lectin receptors [6].
  • ACTH and cortisol levels during residency training [7].
  • These residues can be transplanted onto the cytoplasmic tail of other membrane-bound proteins such that ER residency is conferred [8].
  • Here, we show that the binding of complement-tagged antigens stimulates the translocation of both the BCR and the CD19/CD21 complex into lipid rafts, resulting in prolonged residency in and signaling from the rafts, as compared to BCR cross-linking alone [9].
  • PARTICIPANTS: A total of 125 HCWs (91 hospital employees and 34 house staff or medical students [the physician group]) who had a positive tuberculin skin test between July 1992 and January 1994 and were offered isoniazid preventive therapy [10].

Biological context of Internship and Residency


Anatomical context of Internship and Residency

  • Comparative end organ weights as well as plasma testosterone determinations reported earlier indicated that, with continued intraabdominal residency 3 months and longer, the Leydig cells in this strain of rat became significantly less responsive to stimulation by pituitary gonadotropic hormones [16].
  • Altogether, these results suggest that KKXX and KDEL retrieval motifs have different topological effects on theirs own at steady state: the first results in a specific enrichment in the intermediate compartment and cis-Golgi complex, and the latter dictates residency in the endoplasmic reticulum [17].
  • These findings suggest that Nef alters the normal routing and residencies of the CD4 molecule and that the positive effect of Nef on T cell activation is independent of this modulation [18].
  • After doxycycline is withdrawn, the recombined locus persists for at least 60 days, indicating that recombination has occurred in epithelial cell progenitors that have long residency times in the proliferative units of the intestine (crypts of Lieberkühn) [19].
  • Interestingly, abrogation of Ung activity in M. smegmatis results in nearly a total abolition of their multiplication and a much-decreased residency in macrophages stimulated with interferon gamma [20].

Associations of Internship and Residency with chemical compounds


Gene context of Internship and Residency

  • Dominant active Rap1A, in contrast to Ras, when introduced into epithelial MDCK and MCF-7 cells, does not perturb AF-6-specific residency in cell-cell adhesion complexes [26].
  • Mutation of a consensus nuclear localization signal in MusTRD1/BEN results in a reversal of nuclear residency of the two proteins and a concomitant gain of c-fos promoter activity [27].
  • Regulation of follitropin receptor cell surface residency by the ubiquitin-proteasome pathway [28].
  • The kinetic parameters for the binding, internalization, intracellular residency, and recycling of 125I-labeled transferrin were unchanged by PMA treatment, as were the rate and extent of internalization of anti-receptor antibody [29].
  • SETTING: University-affiliated Veterans Affairs Medical Center. DESIGN: Two internal medicine house staff teams (one PGY-1 [postgraduate year] and one PGY-2 or PGY-3) observed during 5 short call admitting days [30].

Analytical, diagnostic and therapeutic context of Internship and Residency

  • Impact of fellowships on orthopaedic surgery residencies, patient care, and orthopaedic practice. Part I [31].
  • The rotation as incorporated into the geriatrics curriculum of the Family Practice Residency, Knoxville Unit, University of Tennessee College of Medicine, involves all second-year and third-year residents in the medical care for patients of a 222-bed long-term care facility [32].
  • Across the decade there also had been a significant increase in the percentage of IM programs offering structured education in chest auscultation (cardiac auscultation increase, 27.1 to 48% [p < 0.001]; pulmonary auscultation increase, 14.1 to 23.7% [p < 0.02]), but no significant changes for FP residencies [33].
  • The DMFT values were related to the fluoride content in the drinking water, oral hygiene, residency and year of examination [34].
  • Because of the diminishing number of patients diagnosed with otosclerosis, the adequacy of residency training in stapedectomy techniques remains controversial [35].


  1. Distinct roles for matrix metalloproteinase-2 and alpha4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis. Graesser, D., Mahooti, S., Madri, J.A. J. Neuroimmunol. (2000) [Pubmed]
  2. Is living in a rural area good for your respiratory health? Results from a cross-sectional study in Scotland. Iversen, L., Hannaford, P.C., Price, D.B., Godden, D.J. Chest (2005) [Pubmed]
  3. CAD-aided mammogram training. Luo, P., Qian, W., Romilly, P. Academic radiology. (2005) [Pubmed]
  4. A model for teaching ethics in a family practice residency. Self, D.J., Lyon-Loftus, G.T. The Journal of family practice. (1983) [Pubmed]
  5. Association between Balint training and physician empathy and work satisfaction. Cataldo, K.P., Peeden, K., Geesey, M.E., Dickerson, L. Family medicine. (2005) [Pubmed]
  6. Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes. Ohtsubo, K., Takamatsu, S., Minowa, M.T., Yoshida, A., Takeuchi, M., Marth, J.D. Cell (2005) [Pubmed]
  7. ACTH and cortisol levels during residency training. Coeck, C., Jorens, P.G., Vandevivere, J., Mahler, C. N. Engl. J. Med. (1991) [Pubmed]
  8. Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum. Nilsson, T., Jackson, M., Peterson, P.A. Cell (1989) [Pubmed]
  9. The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts. Cherukuri, A., Cheng, P.C., Sohn, H.W., Pierce, S.K. Immunity (2001) [Pubmed]
  10. Acceptance of isoniazid preventive therapy by health care workers after tuberculin skin test conversion. Camins, B.C., Bock, N., Watkins, D.L., Blumberg, H.M. JAMA (1996) [Pubmed]
  11. The use of Part I National Board scores in the selection of residents in ophthalmology and otolaryngology. McCollister, R.J. JAMA (1988) [Pubmed]
  12. Primary care residency training: the first five years. Boufford, J.I. Ann. Intern. Med. (1977) [Pubmed]
  13. National Study of Internal Medicine Manpower: XIX. Trends in internal medicine residency training programs. Andersen, R.M., Lyttle, C.S., Kohrman, C.H., Levey, G.S., Clements, M.M. Ann. Intern. Med. (1992) [Pubmed]
  14. Genomic structure and subcellular localization of MAL, a human T-cell-specific proteolipid protein. Rancaño, C., Rubio, T., Correas, I., Alonso, M.A. J. Biol. Chem. (1994) [Pubmed]
  15. Cytotoxicity and differentiating actions of adriamycin in WEHI-3B D+ leukemia cells. Gamba-Vitalo, C., Blair, O.C., Tritton, T.R., Lane, P.A., Carbone, R., Sartorelli, A.C. Leukemia (1987) [Pubmed]
  16. Effects of cryptorchidy, parabiosis, and estrogen administration upon Leydig cell tumorigenesis in Fischer rats. Huseby, R.A. Cancer Res. (1981) [Pubmed]
  17. A different intracellular distribution of a single reporter protein is determined at steady state by KKXX or KDEL retrieval signals. Lotti, L.V., Mottola, G., Torrisi, M.R., Bonatti, S. J. Biol. Chem. (1999) [Pubmed]
  18. HIV-1 Nef activity in murine T cells. CD4 modulation and positive enhancement. Rhee, S.S., Marsh, J.W. J. Immunol. (1994) [Pubmed]
  19. Inducible gene knockouts in the small intestinal and colonic epithelium. Saam, J.R., Gordon, J.I. J. Biol. Chem. (1999) [Pubmed]
  20. Importance of uracil DNA glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich bacteria, in mutation prevention, tolerance to acidified nitrite, and endurance in mouse macrophages. Venkatesh, J., Kumar, P., Krishna, P.S., Manjunath, R., Varshney, U. J. Biol. Chem. (2003) [Pubmed]
  21. Editorial: Combat zone: Residency training. Mason, H.R. JAMA (1975) [Pubmed]
  22. Analysis of narcotic analgesic usage in the treatment of postoperative pain. Sriwatanakul, K., Weis, O.F., Alloza, J.L., Kelvie, W., Weintraub, M., Lasagna, L. JAMA (1983) [Pubmed]
  23. National Study of Internal Medicine Manpower: VII. Residency and fellowship training 1976-1977 through 1980-1981. Schleiter, M.K., Tarlov, A.R., Weil, P.A. Ann. Intern. Med. (1981) [Pubmed]
  24. Supramolecular recognition: on the kinetic lability of thermodynamically stable host-guest association complexes. Goshe, A.J., Steele, I.M., Ceccarelli, C., Rheingold, A.L., Bosnich, B. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  25. Beta 2 glycoprotein I is a major protein associated with very rapidly cleared liposomes in vivo, suggesting a significant role in the immune clearance of "non-self" particles. Chonn, A., Semple, S.C., Cullis, P.R. J. Biol. Chem. (1995) [Pubmed]
  26. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Boettner, B., Govek, E.E., Cross, J., Van Aelst, L. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  27. Repression of TFII-I-dependent transcription by nuclear exclusion. Tussié-Luna, M.I., Bayarsaihan, D., Ruddle, F.H., Roy, A.L. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  28. Regulation of follitropin receptor cell surface residency by the ubiquitin-proteasome pathway. Cohen, B.D., Bariteau, J.T., Magenis, L.M., Dias, J.A. Endocrinology (2003) [Pubmed]
  29. Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester. Klausner, R.D., Harford, J., van Renswoude, J. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  30. Are things different in the light of day? A time study of internal medicine house staff days. Parenti, C., Lurie, N. Am. J. Med. (1993) [Pubmed]
  31. Impact of fellowships on orthopaedic surgery residencies, patient care, and orthopaedic practice. Part I. Cooper, R.R. The Journal of bone and joint surgery. American volume. (1998) [Pubmed]
  32. A nursing home rotation in a family practice residency. Moon, J.B., Davis, L.E., Eaddy, J.A., Shacklett, G.E., Stockton, M.D. The Journal of family practice. (1990) [Pubmed]
  33. The teaching of chest auscultation during primary care training: has anything changed in the 1990s? Mangione, S., Duffy, F.D. Chest (2003) [Pubmed]
  34. Factors influencing the caries decline in Lithuanian adolescents--trends in the period 1993-2001. Aleksejūniene, J., Holst, D., Balciūniene, I. Eur. J. Oral Sci. (2004) [Pubmed]
  35. Prospective study of resident-performed stapedectomy. Backous, D.D., Coker, N.J., Jenkins, H.A. The American journal of otology. (1993) [Pubmed]
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