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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Poxvirus preparation CONPIND initiates production of the major inflammatory mediators IL-1 alpha and TNF-alpha in human whole blood and in blood mononuclear cell cultures.

The poxvirus preparation CONPIND initiated the production of the two major inflammatory mediators interleukin-1 alpha (IL-1 alpha) and tumour necrosis factor-alpha (TNF-alpha) in whole blood and in blood mononuclear cell cultures of man at 37 degrees C within 12-48 h. The release of the cytokines followed a dose-efficacy curve. High levels of IL1-alpha (up to 810 pg/ml) and TNF-alpha (up to 533 pg/ml) were determined by sandwich enzyme-linked immunosorbent assay.[1]

References

  1. Poxvirus preparation CONPIND initiates production of the major inflammatory mediators IL-1 alpha and TNF-alpha in human whole blood and in blood mononuclear cell cultures. Ahne, W., Mayr, A. Comp. Immunol. Microbiol. Infect. Dis. (1997) [Pubmed]
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