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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Dystonic reaction to a phenothiazine presenting as Bell's palsy.

An 11-year-old boy presented to the pediatric ED with signs and symptoms of Bell's palsy, which was believed to be a result of otitis media. He subsequently began to list to the left and could not walk erect. Because of a history of prochlorperazine use for vomiting, a diagnosis of a dystonic reaction to a phenothiazine was made, and the patient was treated with intravenous diphenhydramine. All symptoms resolved, including seventh nerve palsy, within 5 minutes of treatment. Medications are often prescribed by physicians for vomiting without caretakers being aware of the side-effects. Dystonic reactions can be severe and present with myriad neurologic signs and symptoms.[1]


  1. Dystonic reaction to a phenothiazine presenting as Bell's palsy. Bhopale, S., Seidel, J.S. Annals of emergency medicine. (1997) [Pubmed]
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