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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage lambda.

oop RNA, which is initiated at the po promoter and is 81 nucleotides long, can function as a leader sequence for the lambda immunity establishment transcription, previously believed to originate at a special promoter pre located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle as a primer for the initiation of lambda DNA replication, or leading to the establishment of lysogeny when elongated into the imm transcript, which directs synthesis of the repressor.[1]

References

  1. 4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage lambda. Honigman, A., Hu, S.L., Chase, R., Szybalski, W. Nature (1976) [Pubmed]
 
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