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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chiral resolution of flobufen by high performance liquid chromatography and capillary electrophoresis.

The enantiomeric separation of an anti-inflammatory drug flobufen was performed on various chiral columns in liquid chromatography and by reversed phase chromatography and by capillary electrophoresis with beta-cyclodextrin as a chiral selector in the mobile phase and background electrolyte, respectively. The elution order of individual enantiomers is discussed with respect to the absolute chirality of (+/-)-flobufen determined by X-ray crystallography.[1]

References

  1. Chiral resolution of flobufen by high performance liquid chromatography and capillary electrophoresis. Tesarvá, E., Gilar, M., Jegorov, A., Uhrová, M., Deyl, Z. Biomed. Chromatogr. (1997) [Pubmed]
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