- IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. Deveraux, Q.L., Roy, N., Stennicke, H.R., Van Arsdale, T., Zhou, Q., Srinivasula, S.M., Alnemri, E.S., Salvesen, G.S., Reed, J.C. EMBO J. (1998)