- Lipid-free apolipoprotein (apo) A-I is converted into alpha-migrating high density lipoproteins by lipoprotein-depleted plasma of normolipidemic donors and apo A-I-deficient patients but not of Tangier disease patients. von Eckardstein, A., Huang, Y., Kastelein, J.J., Geisel, J., Real, J.T., Kuivenhoven, J.A., Miccoli, R., Noseda, G., Assmann, G. Atherosclerosis (1998)