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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Barley oxalate oxidase is a hexameric protein related to seed storage proteins: evidence from X-ray crystallography.

The oxalate oxidase enzyme expressed in barley roots is a thermostable, protease-resistant enzyme that generates H2O2. It has great medical importance because of its use to assay plasma and urinary oxalate, and it has also been used to generate transgenic, pathogen-resistant crops. This protein has now been purified and three types of crystals grown. X-ray analysis shows that the symmetry present in these crystals is consistent with a hexameric arrangement of subunits, probably a trimer of dimers. This structure may be similar to that found in the related seed storage proteins.[1]

References

  1. Barley oxalate oxidase is a hexameric protein related to seed storage proteins: evidence from X-ray crystallography. Woo, E.J., Dunwell, J.M., Goodenough, P.W., Pickersgill, R.W. FEBS Lett. (1998) [Pubmed]
 
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