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Chemical Compound Review

Celeport     4-(2-benzylphenoxy)butyl- methyl-azanium...

Synonyms: Alnert, Bifemelane HCl, MCI-2016, SureCN1648821, AC1L2AVF, ...
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Disease relevance of Bifemelane

 

Psychiatry related information on Bifemelane

 

High impact information on Bifemelane

 

Chemical compound and disease context of Bifemelane

 

Biological context of Bifemelane

 

Anatomical context of Bifemelane

 

Associations of Bifemelane with other chemical compounds

 

Gene context of Bifemelane

 

Analytical, diagnostic and therapeutic context of Bifemelane

References

  1. Post-ischemic administration of bifemelane hydrochloride prohibits ischemia-induced depletion of the muscarinic M1-receptor and its mRNA in the gerbil hippocampus. Ogawa, N., Asanuma, M., Mizukawa, K., Hirata, H., Chou, H., Mori, A. Brain Res. (1992) [Pubmed]
  2. Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Nomoto, M., Irifune, M., Fukuzaki, K., Fukuda, T. Neurosci. Lett. (1994) [Pubmed]
  3. Effects of bifemelane hydrochloride (MCI-2016) on acetylcholine level reduced by scopolamine, hypoxia and ischemia in the rats and mongolian gerbils. Saito, K., Honda, S., Tobe, A., Yanagiya, I. Jpn. J. Pharmacol. (1985) [Pubmed]
  4. Effects of bifemelane hydrochloride (MCI-2016) on acetylcholine and norepinephrine release from cortical slices of bilaterally carotid-artery-ligated Mongolian gerbils. Saito, K., Honda, S., Egawa, M., Tobe, A. Jpn. J. Pharmacol. (1985) [Pubmed]
  5. Bifemelane hydrochloride protects against cytotoxicity of hydrogen peroxide on cultured rat neuroblastoma cell line. Miyazaki, I., Iwata-Ichikawa, E., Asanuma, M., Iida, M., Ogawa, N. Neurochem. Res. (1999) [Pubmed]
  6. Horizontal component of electro-oculogram as a parameter of arousal in dementia: relationship between intellectual improvement and increasing arousal under pharmacotherapy. Shigeta, M., Nishikawa, Y., Shimizu, M., Usui, M., Hyoki, K., Kawamuro, Y. Journal of clinical pharmacology. (1993) [Pubmed]
  7. Responders and non-responders to bifemelane hydrochloride in Alzheimer-type and multi-infarct dementia. Shigeta, M., Nishikawa, Y., Shimizu, M., Usui, M., Hyoki, K., Kawamuro, Y. International clinical psychopharmacology. (1993) [Pubmed]
  8. The clinical effect of bifemelane hydrochloride on dementia in aged patients. Yamagami, S., Mui, K., Hirayama, E., Furutsuka, D., Soma, T., Soejima, S., Nishiwaki, S., Kiriike, N., Boku, S. Drugs under experimental and clinical research. (1991) [Pubmed]
  9. Effects of bifemelane hydrochloride on cortical neuronal activity in cats. Egawa, M., Ikegami, S., Hanada, Y., Tobe, A. Neuropharmacology (1987) [Pubmed]
  10. Selective potentiation of noradrenaline in the guinea-pig vas deferens by 2-(4-methylaminobutoxy) diphenylmethane hydrochloride (MCI-2016), a new psychotropic drug. Ohizumi, Y., Takahashi, M., Tobe, A. Br. J. Pharmacol. (1982) [Pubmed]
  11. The effect of long-term post-ischemic bifemelane hydrochloride treatment on cholinergic systems in the gerbil hippocampus. Huang, Y.L., Onodera, H., Takeda, A., Itoyama, Y., Kogure, K. Brain Res. (1996) [Pubmed]
  12. Use of bifemelane hydrochloride in improving and maintaining the visual field of patients with glaucoma. Shigemitsu, T., Majima, Y. Clinical therapeutics. (1996) [Pubmed]
  13. Effect of vagal autotransplantation and bifemelane hydrochloride on cholinergic markers and event-related potentials in rats with lesions of the nucleus basalis magnocellularis. Ikeda, K., Egashira, T., Yamashita, J., Okoyama, S. Brain Res. (1995) [Pubmed]
  14. Effect of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016) on the scopolamine-induced deficit of spontaneous alternation behavior in rats. Tobe, A., Egawa, M., Nagai, R. Jpn. J. Pharmacol. (1983) [Pubmed]
  15. Treatment with bifemelane for optic nerve damage following high intraocular pressure in rat eyes. Adachi, M., Takahashi, K., Yuge, K., Nishikawa, M., Miki, H., Uyama, M. European journal of ophthalmology. (1996) [Pubmed]
  16. Effects of bifemelane hydrochloride on loss of N-methyl-D-aspartate receptor and muscarinic cholinergic receptor binding in the gerbil hippocampus after transient ischemia. Asanuma, M., Ogawa, N., Haba, K., Hirata, H., Chou, H., Mori, A. Archives internationales de pharmacodynamie et de thérapie. (1992) [Pubmed]
  17. Protective effect of bifemelane on c-Fos-like immunoreactivity in rat cerebral ischemia. Gu, G.Z., Mizushima, H., Arai, Y., Shimazu, M., Matsumoto, K., Shioda, S., Nakai, Y. Brain Res. Bull. (1994) [Pubmed]
  18. Bifemelane hydrochloride enhances 'ischemic tolerance' phenomenon in gerbil hippocampal CA1 neurons. Ohtsuki, T., Matsumoto, M., Taguchi, A., Yang, G.M., Mabuchi, T., Matsushita, K., Kuwabara, K., Kitagawa, K., Yanagihara, T. Life Sci. (1996) [Pubmed]
  19. Inhibitory effect of bifemelane on superoxide generation by activated neutrophils measured using a simple chemiluminescence method. Yoshida, T., Sotomatsu, A., Tanaka, M., Hirai, S. Free Radic. Res. (1994) [Pubmed]
  20. Bifemelane in the treatment of central retinal artery or vein obstruction. Hirayama, Y., Matsunaga, N., Tashiro, J., Amemiya, T., Iwasaki, M. Clinical therapeutics. (1990) [Pubmed]
  21. Protective effect of bifemelane hydrochloride on ischemic hippocampal CA1 neuronal damage in the gerbil: relation to induction of HSP70. Liu, X.H., Abe, K., Aoki, M., Lee, T.H., Kato, H., Kogure, K. Life Sci. (1993) [Pubmed]
  22. Bifemelane hydrochloride reduces plasma beta-endorphin-like immunoreactivity levels in rats. Mitsuma, T., Hirooka, Y., Yuasa, K., Nogimori, T. Exp. Clin. Endocrinol. (1990) [Pubmed]
  23. Free radical scavenging by bifemelane hydrochloride and its major metabolites. Liu, J., Ogawa, N., Wang, X., Mori, A. Archives internationales de pharmacodynamie et de thérapie. (1991) [Pubmed]
  24. Reduction of HSP70 and HSC70 mRNA inductions by bifemelane hydrochloride after transient ischemia in gerbil brain. Aoki, M., Abe, K., Liu, X.H., Lee, T.H., Kato, H., Kogure, K. Neurosci. Lett. (1993) [Pubmed]
  25. Ischemia-induced changes in alpha-tubulin and beta-actin mRNA in the gerbil brain and effects of bifemelane hydrochloride. Asanuma, M., Ogawa, N., Hirata, H., Chou, H.H., Kondo, Y., Mori, A. Brain Res. (1993) [Pubmed]
  26. Effects of bifemelane hydrochloride on various cholinergic markers in cortical and subcortical regions of aged rats. Egashira, T., Nagai, T., Kimba, Y., Takano, R., Yamanaka, Y. Jpn. J. Pharmacol. (1989) [Pubmed]
  27. Effects of bifemelane hydrochloride on cerebral circulation and metabolism in patients with aphasia. Kabasawa, H., Matsubara, M., Kamimoto, K., Hibino, H., Banno, T., Nagai, H. Clinical therapeutics. (1994) [Pubmed]
 
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