The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Pnmt  -  phenylethanolamine-N-methyltransferase

Mus musculus

Synonyms: Noradrenaline N-methyltransferase, PNMTase, Pent, Phenylethanolamine N-methyltransferase
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Pnmt

 

Psychiatry related information on Pnmt

  • Both PNMT inhibitors showed dose-related reductions in exploratory head-dipping but were without effect on locomotor activity [4].
 

High impact information on Pnmt

 

Chemical compound and disease context of Pnmt

 

Biological context of Pnmt

 

Anatomical context of Pnmt

 

Associations of Pnmt with chemical compounds

 

Other interactions of Pnmt

 

Analytical, diagnostic and therapeutic context of Pnmt

References

  1. Animal models of pheochromocytoma. Tischler, A.S., Powers, J.F., Alroy, J. Histol. Histopathol. (2004) [Pubmed]
  2. Functional consequences of oncogene-induced horizontal cell degeneration in the retinas of transgenic mice. Peachey, N.S., Roveri, L., Messing, A., McCall, M.A. Vis. Neurosci. (1997) [Pubmed]
  3. Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice. Powers, J.F., Evinger, M.J., Tsokas, P., Bedri, S., Alroy, J., Shahsavari, M., Tischler, A.S. Cell Tissue Res. (2000) [Pubmed]
  4. Behavioral effects of the inhibitors of phenylethanolamine-N-methyltransferase, LY 78335 and LY 134046, and their interactions with ethanol. Durcan, M.J., Lister, R.G., Linnoila, M. Psychopharmacology (Berl.) (1990) [Pubmed]
  5. Developmental abnormalities in transgenic mice expressing a sialic acid-specific 9-O-acetylesterase. Varki, A., Hooshmand, F., Diaz, S., Varki, N.M., Hedrick, S.M. Cell (1991) [Pubmed]
  6. The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Mercer, E.H., Hoyle, G.W., Kapur, R.P., Brinster, R.L., Palmiter, R.D. Neuron (1991) [Pubmed]
  7. Rabbit lung indolethylamine N-methyltransferase. cDNA and gene cloning and characterization. Thompson, M.A., Weinshilboum, R.M. J. Biol. Chem. (1998) [Pubmed]
  8. Chromaffin cell function and structure is impaired in corticotropin-releasing hormone receptor type 1-null mice. Yoshida-Hiroi, M., Bradbury, M.J., Eisenhofer, G., Hiroi, N., Vale, W.W., Novotny, G.E., Hartwig, H.G., Scherbaum, W.A., Bornstein, S.R. Mol. Psychiatry (2002) [Pubmed]
  9. Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice. Cadd, G.G., Hoyle, G.W., Quaife, C.J., Marck, B., Matsumoto, A.M., Brinster, R.L., Palmiter, R.D. Mol. Endocrinol. (1992) [Pubmed]
  10. The effects of two different inhibitors of PNMT and their interactions with ethanol. Durcan, M.J., Lister, R.G., Linnoila, M. Neuroreport (1992) [Pubmed]
  11. Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice. Kubovcakova, L., Tybitanclova, K., Sabban, E.L., Majzoub, J., Zorad, S., Vietor, I., Wagner, E.F., Krizanova, O., Kvetnansky, R. Ann. N. Y. Acad. Sci. (2004) [Pubmed]
  12. Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase. Morita, S., Kobayashi, K., Hidaka, H., Nagatsu, T. Brain Res. Mol. Brain Res. (1992) [Pubmed]
  13. Cloning and base sequence analysis of a cDNA encoding mouse lung thioether S-methyltransferase. Warner, D.R., Mozier, N.M., Pearson, J.D., Hoffman, J.L. Biochim. Biophys. Acta (1995) [Pubmed]
  14. Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice. Jeong, K.H., Jacobson, L., Pacák, K., Widmaier, E.P., Goldstein, D.S., Majzoub, J.A. Endocrinology (2000) [Pubmed]
  15. Increased body fat mass and suppression of circulating leptin levels in response to hypersecretion of epinephrine in phenylethanolamine-N-methyltransferase (PNMT)-overexpressing mice. Böttner, A., Haidan, A., Eisenhofer, G., Kristensen, K., Castle, A.L., Scherbaum, W.A., Schneider, H., Chrousos, G.P., Bornstein, S.R. Endocrinology (2000) [Pubmed]
  16. Immunohistochemical and histochemical evidence for the presence of noradrenaline, serotonin and gamma-aminobutyric acid in chief cells of the mouse carotid body. Oomori, Y., Nakaya, K., Tanaka, H., Iuchi, H., Ishikawa, K., Satoh, Y., Ono, K. Cell Tissue Res. (1994) [Pubmed]
  17. Comparative studies of PC12 and mouse pheochromocytoma-derived rodent cell lines as models for the study of neuroendocrine systems. Dixon, D.N., Loxley, R.A., Barron, A., Cleary, S., Phillips, J.K. In Vitro Cell. Dev. Biol. Anim. (2005) [Pubmed]
  18. Phenylethanolamine-N-methyltransferase - immunoreactive nerve terminals afferent to the mouse substantia nigra. Nagatsu, I., Ikemoto, K., Takeuchi, T., Arai, R., Karasawa, N., Fujii, T., Nagatsu, T. Neurosci. Lett. (1998) [Pubmed]
  19. Adrenal 11 beta-hydroxysteroid dehydrogenase. Shimojo, M., Condon, J., Whorwood, C.B., Stewart, P.M. Endocr. Res. (1996) [Pubmed]
  20. Identification of phenylethanolamine N-methyltransferase gene expression in stellate ganglia and its modulation by stress. Kubovcakova, L., Micutkova, L., Bartosova, Z., Sabban, E.L., Krizanova, O., Kvetnansky, R. J. Neurochem. (2006) [Pubmed]
  21. Inhibitors of phenylethanolamine N-methyltransferase and epinephrine biosynthesis. 2. 1,2,3,4-Tetrahydroisoquinoline-7-sulfonanilides. Blank, B., Krog, A.J., Weiner, G., Pendleton, R.G. J. Med. Chem. (1980) [Pubmed]
  22. Midkine is a potent regulator of the catecholamine biosynthesis pathway in mouse aorta. Ezquerra, L., Herradon, G., Nguyen, T., Silos-Santiago, I., Deuel, T.F. Life Sci. (2006) [Pubmed]
  23. Human indolethylamine N-methyltransferase: cDNA cloning and expression, gene cloning, and chromosomal localization. Thompson, M.A., Moon, E., Kim, U.J., Xu, J., Siciliano, M.J., Weinshilboum, R.M. Genomics (1999) [Pubmed]
  24. Reduction of adrenal and kidney epinephrine and phenylethanolamine N-methyltransferase in AP-2 knockout mouse fetuses. Kennedy, B., Enns, R., Nelson, D., Williams, T., Bao, X., Ziegler, M.G. Ann. N. Y. Acad. Sci. (2002) [Pubmed]
  25. Comparative study of catecholamine synthesizing enzymes in adrenal medulla of CRH knock-out mice, their CRH (+/+) mates and Sprague-Dawley rats. Kubovcáková, L., Sabban, E.L., Kvetnansky, R., Krizanova, O. Endocrine regulations. (2002) [Pubmed]
  26. Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I. Nomura, T., Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Hagino, Y., Ota, A., Nakashima, A., Mori, K., Sugimoto, T., Ueno, O., Nozawa, Y., Ichinose, H., Nagatsu, T. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (1998) [Pubmed]
 
WikiGenes - Universities