Gene Review:
NUP88 - nucleoporin 88kDa
Homo sapiens
Synonyms:
88 kDa nucleoporin, MGC8530, Nuclear pore complex protein Nup88, Nucleoporin Nup88
- Nup88 mRNA overexpression is associated with high aggressiveness of breast cancer. Agudo, D., Gómez-Esquer, F., Martínez-Arribas, F., Núñez-Villar, M.J., Pollán, M., Schneider, J. Int. J. Cancer (2004)
- Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes--a speculation of separate pathways in initiation of melanoma. Zhang, H., Rosdahl, I. Carcinogenesis (2003)
- Clinicopathological significance of Nup88 expression in patients with colorectal cancer. Emterling, A., Skoglund, J., Arbman, G., Schneider, J., Evertsson, S., Carstensen, J., Zhang, H., Sun, X.F. Oncology (2003)
- Nucleoporin 88 expression in hepatitis B and C virus-related liver diseases. Knoess, M., Kurz, A.K., Goreva, O., Bektas, N., Breuhahn, K., Odenthal, M., Schirmacher, P., Dienes, H.P., Bock, C.T., Zentgraf, H., Zur Hausen, A. World J. Gastroenterol. (2006)
- The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. Fornerod, M., van Deursen, J., van Baal, S., Reynolds, A., Davis, D., Murti, K.G., Fransen, J., Grosveld, G. EMBO J. (1997)
- Nup214 is required for CRM1-dependent nuclear protein export in vivo. Hutten, S., Kehlenbach, R.H. Mol. Cell. Biol. (2006)
- Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis. Boer, J., Bonten-Surtel, J., Grosveld, G. Mol. Cell. Biol. (1998)
- The nuclear pore complex protein Nup88 is overexpressed in tumor cells. Martínez, N., Alonso, A., Moragues, M.D., Pontón, J., Schneider, J. Cancer Res. (1999)
- Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes. Griffis, E.R., Xu, S., Powers, M.A. Mol. Biol. Cell (2003)
- Developing chick embryos express a protein which shares homology with the nuclear pore complex protein Nup88 present in human tumors. Schneider, J., Linares, R., Martínez-Arribas, F., Moragues, M.D., Nuñez-Villar, M.J., Palomar, M.A., Pontón, J. Int. J. Dev. Biol. (2004)
- Deguelin regulates nuclear pore complex proteins Nup98 and Nup88 in U937 cells in vitro. Liu, H.L., Chen, Y., Cui, G.H., Wu, Q.L., He, J., Chen, W.H., Zhou, J.F. Acta Pharmacol. Sin. (2005)
- The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor. Takano, H., Gusella, J.F. BMC neuroscience [electronic resource]. (2002)
- Expression of p16, p27, p53, p73 and Nup88 proteins in matched primary and metastatic melanoma cells. Zhang, H., Schneider, J., Rosdahl, I. Int. J. Oncol. (2002)
- Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export. Bernad, R., van der Velde, H., Fornerod, M., Pickersgill, H. Mol. Cell. Biol. (2004)