Gene Review:
SLC5A7 - solute carrier family 5 (sodium/choline...
Homo sapiens
Synonyms:
CHT, CHT1, HMN7A, Hemicholinium-3-sensitive choline transporter, High affinity choline transporter 1, ...
- The high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice. Bazalakova, M.H., Blakely, R.D. Handbook of experimental pharmacology. (2006)
- Postmenopausal hormone therapy and breast cancer: a systematic review and meta-analysis. Shah, N.R., Borenstein, J., Dubois, R.W. Menopause (New York, N.Y.) (2005)
- Low-dose continuous oral fosfestrol is highly active in 'hormone-refractory' prostate cancer. Orlando, M., Chacón, M., Salum, G., Chacón, D.R. Ann. Oncol. (2000)
- Long-term results of intraoperative presacral electron boost radiotherapy (IOERT) in combination with total mesorectal excision (TME) and chemoradiation in patients with locally advanced rectal cancer. Krempien, R., Roeder, F., Oertel, S., Roebel, M., Weitz, J., Hensley, F.W., Timke, C., Funk, A., Bischof, M., Zabel-Du Bois, A., Niethammer, A.G., Eble, M.J., Buchler, M.W., Treiber, M., Debus, J. Int. J. Radiat. Oncol. Biol. Phys. (2006)
- Accelerated hemopoietic recovery after chemotherapy and autologous bone marrow transplantation in hematological malignancies using recombinant GM-CSF: preliminary results obtained in 14 cases. Visani, G., Tosi, P., Gamberi, B., Cenacchi, A., Mazzanti, P., Stabilini, C., Bandini, G., Mazza, P., Gherlinzoni, F., Cavo, M. Haematologica (1990)
- Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. Slotkin, T.A., Nemeroff, C.B., Bissette, G., Seidler, F.J. J. Clin. Invest. (1994)
- Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice. Payette, D.J., Xie, J., Guo, Q. Brain Res. (2007)
- Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane. Xie, J., Guo, Q. J. Biol. Chem. (2004)
- Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate. Okuda, T., Okamura, M., Kaitsuka, C., Haga, T., Gurwitz, D. J. Biol. Chem. (2002)
- Cortical choline transporter function measured in vivo using choline-sensitive microelectrodes: clearance of endogenous and exogenous choline and effects of removal of cholinergic terminals. Parikh, V., Sarter, M. J. Neurochem. (2006)
- The "ins" and "outs" of the high-affinity choline transporter CHT1. Ribeiro, F.M., Black, S.A., Prado, V.F., Rylett, R.J., Ferguson, S.S., Prado, M.A. J. Neurochem. (2006)
- Changes of thymidine kinase (TK) during adjuvant and palliative chemotherapy. Topolcan, O., Holubec, L., Finek, J., Stieber, P., Holdenrieder, S., Lamerz, R., Holubec Sen, L., Svobodova, S., Visokai, V., Lipska, L. Anticancer Res. (2005)
- Functional characterization of the human high-affinity choline transporter. Okuda, T., Haga, T. FEBS Lett. (2000)
- Molecular cloning of a human, hemicholinium-3-sensitive choline transporter. Apparsundaram, S., Ferguson, S.M., George, A.L., Blakely, R.D. Biochem. Biophys. Res. Commun. (2000)
- Binding of [3H]hemicholinium-3 to the high-affinity choline transporter in electric organ synaptosomal membranes. O'Regan, S. J. Neurochem. (1988)
- SEC14-like protein 1 interacts with cholinergic transporters. Ribeiro, F.M., Ferreira, L.T., Marion, S., Fontes, S., Gomez, M., Ferguson, S.S., Prado, M.A., Prado, V.F. Neurochem. Int. (2007)
- The hemicholinium-3 sensitive high affinity choline transporter is internalized by clathrin-mediated endocytosis and is present in endosomes and synaptic vesicles. Ribeiro, F.M., Alves-Silva, J., Volknandt, W., Martins-Silva, C., Mahmud, H., Wilhelm, A., Gomez, M.V., Rylett, R.J., Ferguson, S.S., Prado, V.F., Prado, M.A. J. Neurochem. (2003)
- Localization of cholinergic innervation in guinea pig heart by immunohistochemistry for high-affinity choline transporters. Hoover, D.B., Ganote, C.E., Ferguson, S.M., Blakely, R.D., Parsons, R.L. Cardiovasc. Res. (2004)
- Neoadjuvant docetaxel, cisplatin, 5-fluorouracil before concurrent chemoradiotherapy in locally advanced squamous cell carcinoma of the head and neck versus concomitant chemoradiotherapy: a phase II feasibility study. Ghi, M.G., Paccagnella, A., D'Amanzo, P., Mione, C.A., Fasan, S., Paro, S., Mastromauro, C., Carnuccio, R., Turcato, G., Gatti, C., Pallini, A., Nascimben, O., Biason, R., Oniga, F., Medici, M., Rossi, F., Fila, G. Int. J. Radiat. Oncol. Biol. Phys. (2004)
- Management of primary anal canal adenocarcinoma: a large retrospective study from the Rare Cancer Network. Belkacémi, Y., Berger, C., Poortmans, P., Piel, G., Zouhair, A., Méric, J.B., Nguyen, T.D., Krengli, M., Behrensmeier, F., Allal, A., De Looze, D., Bernier, J., Scandolaro, L., Mirimanoff, R.O. Int. J. Radiat. Oncol. Biol. Phys. (2003)