Your search matched a total of 73 documents. Results 1 - 10.
Caenorhabditis elegans
Gene: ... decrease in CTD phosphorylation and embryonic transcription, and severe loss of cdk- 7 activity blocks all...High impact information on cdk- 7 cdk- 7 Is required for mRNA transcription and cell cycle... in Caenorhabditis elegans cdk- 7 and have used it to analyze the role of cdk- 7 in embryonic blastomeres, where cell...
Drosophila melanogaster
Gene: ... High impact information on Cdk7 Vertebrate Cdk7 is also known to be part of TFIIH. T- loop phosphorylation stabilizes the CDK7- cyclin H- MAT1 complex in vivo and regulates its CTD kinase activity. Mutation of both phosphorylation sites causes temperature- dependent dissociation of CDK7 complexes... / Synonyms: CDK7; DmCDK7; DmCdk7
Homo sapiens
Gene: ... Disease relevance of CDK7 HIV- 1 Tat- associated RNA polymerase C- terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat- mediated transcription. Cyclin- dependent kinase activating kinase/ Cdk7... on CDK7 We demonstrate that the XPD mutation alters cdk7 function in RARalpha phosphorylation. However...
Xenopus (Silurana) tropicalis
Gene: ... High impact information on cdk7 In the absence of MAT- 1, phosphorylation of the T- loop appears to be required for cdk7 to bind cyclin H. Phosphorylation of both residues does not require cyclin H binding...RNAs encoding Xenopus cdk7, cyclin H and MAT1. However, CAK may also exist in oocytes as heterodimeric complexes...
Rattus norvegicus
Gene: ... and mRNAs corresponding to all other Cdks examined( Cdk2, Cdk4, Cdk7, Cdk8) throughout...High impact information on Cdk7 In addition, 17N Ras markedly inhibited phosphorylation of the C... by down- regulation of its principal kinase, cyclin- dependent kinase 7( Cdk7). Cdk6 and Cdk7 activities...
Mus musculus
Gene: ... Disease relevance of Cdk7 A variant mouse plasmacytoma( MPC )- associated translocation chromosome... chromosome in the CAK TEPC 1198 mouse plasmacytoma, as described earlier. High impact information on Cdk7... activating residue of CDK7. Levels of the cdk inhibitor p27Klp1 increase in cAMP- treated cells, and its...
Homo sapiens
Gene: ... CDK7- CycH switched its substrate preference to favour the pol II large subunit C- terminal domain... for CDK7- CycH, also acts to modulate CAK substrate specificity. Sequencing of MAT1 reveals a putative... for ternary complex formation with CDK7- cyclin H. Chemical compound and disease context of MNAT1 Members... / Synonyms: CDK7/cyclin-H assembly factor
MeSH term: ... at this stage. We have isolated a temperature- sensitive mutation in Caenorhabditis elegans cdk- 7 and have used it to analyze the role of cdk- 7 in embryonic blastomeres, where cell cycle progression is independent... is sequentially restricted to this blastomere. By contrast, glp- 1 mRNA is present in all blastomeres until the 8...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
