Gene Review:
MNAT1 - MNAT CDK-activating kinase assembly factor 1
Homo sapiens
Synonyms:
CAP35, CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, MAT1, ...
- Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity. Fikrig, E., Barthold, S.W., Sun, W., Feng, W., Telford, S.R., Flavell, R.A. Immunity (1997)
- Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation. Martinou, I., Fernandez, P.A., Missotten, M., White, E., Allet, B., Sadoul, R., Martinou, J.C. J. Cell Biol. (1995)
- RNA antisense abrogation of MAT1 induces G1 phase arrest and triggers apoptosis in aortic smooth muscle cells. Wu, L., Chen, P., Hwang, J.J., Barsky, L.W., Weinberg, K.I., Jong, A., Starnes, V.A. J. Biol. Chem. (1999)
- Varicella-zoster virus p32/p36 complex is present in both the viral capsid and the nuclear matrix of the infected cell. Friedrichs, W.E., Grose, C. J. Virol. (1986)
- A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death. Sahlgren, C.M., Pallari, H.M., He, T., Chou, Y.H., Goldman, R.D., Eriksson, J.E. EMBO J. (2006)
- The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model. Inoue, H., Tsukita, K., Iwasato, T., Suzuki, Y., Tomioka, M., Tateno, M., Nagao, M., Kawata, A., Saido, T.C., Miura, M., Misawa, H., Itohara, S., Takahashi, R. EMBO J. (2003)
- Regulation of CDK7 substrate specificity by MAT1 and TFIIH. Yankulov, K.Y., Bentley, D.L. EMBO J. (1997)
- In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. Tassan, J.P., Jaquenoud, M., Fry, A.M., Frutiger, S., Hughes, G.J., Nigg, E.A. EMBO J. (1995)
- Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus. Means, J.C., Penabaz, T., Clem, R.J. Virology (2007)
- Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis. Long, J.J., Leresche, A., Kriwacki, R.W., Gottesfeld, J.M. Mol. Cell. Biol. (1998)
- The MAT1 cyclin-dependent kinase-activating kinase (CAK) assembly/targeting factor interacts physically with the MCM7 DNA licensing factor. Wang, Y., Xu, F., Hall, F.L. FEBS Lett. (2000)
- The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway. Sah, N.K., Taneja, T.K., Pathak, N., Begum, R., Athar, M., Hasnain, S.E. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis. De Souza, P.M., Kankaanranta, H., Michael, A., Barnes, P.J., Giembycz, M.A., Lindsay, M.A. Blood (2002)
- Intermediate filaments control the intracellular distribution of caspases during apoptosis. Dinsdale, D., Lee, J.C., Dewson, G., Cohen, G.M., Peter, M.E. Am. J. Pathol. (2004)
- The chicken anemia virus-derived protein apoptin requires activation of caspases for induction of apoptosis in human tumor cells. Danen-van Oorschot, A.A., van Der Eb, A.J., Noteborn, M.H. J. Virol. (2000)
- Molecular cloning of CDK7-associated human MAT1, a cyclin-dependent kinase-activating kinase (CAK) assembly factor. Yee, A., Nichols, M.A., Wu, L., Hall, F.L., Kobayashi, R., Xiong, Y. Cancer Res. (1995)
- MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions. Talukder, A.H., Mishra, S.K., Mandal, M., Balasenthil, S., Mehta, S., Sahin, A.A., Barnes, C.J., Kumar, R. J. Biol. Chem. (2003)
- Retinoid-induced G1 arrest and differentiation activation are associated with a switch to cyclin-dependent kinase-activating kinase hypophosphorylation of retinoic acid receptor alpha. Wang, J., Barsky, L.W., Shum, C.H., Jong, A., Weinberg, K.I., Collins, S.J., Triche, T.J., Wu, L. J. Biol. Chem. (2002)
- Repeating sequence homologies in the p36 target protein of retroviral protein kinases and lipocortin, the p37 inhibitor of phospholipase A2. Weber, K., Johnsson, N. FEBS Lett. (1986)
- The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors. Inamoto, S., Segil, N., Pan, Z.Q., Kimura, M., Roeder, R.G. J. Biol. Chem. (1997)
- Ménage-à-Trois 1 Is Critical for the Transcriptional Function of PPARgamma Coactivator 1. Sano, M., Izumi, Y., Helenius, K., Asakura, M., Rossi, D.J., Xie, M., Taffet, G., Hu, L., Pautler, R.G., Wilson, C.R., Boudina, S., Abel, E.D., Taegtmeyer, H., Scaglia, F., Graham, B.H., Kralli, A., Shimizu, N., Tanaka, H., Mäkelä, T.P., Schneider, M.D. Cell Metab. (2007)
- Retinoic acid induces leukemia cell G1 arrest and transition into differentiation by inhibiting cyclin-dependent kinase-activating kinase binding and phosphorylation of PML/RARalpha. Wang, J.G., Barsky, L.W., Davicioni, E., Weinberg, K.I., Triche, T.J., Zhang, X.K., Wu, L. FASEB J. (2006)
- p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner. Ko, L.J., Shieh, S.Y., Chen, X., Jayaraman, L., Tamai, K., Taya, Y., Prives, C., Pan, Z.Q. Mol. Cell. Biol. (1997)
- Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex. Bochar, D.A., Pan, Z.Q., Knights, R., Fisher, R.P., Shilatifard, A., Shiekhattar, R. J. Biol. Chem. (1999)
- CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs? Lolli, G., Johnson, L.N. Cell Cycle (2005)
- Blocking caspase-activated apoptosis improves contractility in failing myocardium. Laugwitz, K.L., Moretti, A., Weig, H.J., Gillitzer, A., Pinkernell, K., Ott, T., Pragst, I., Städele, C., Seyfarth, M., Schömig, A., Ungerer, M. Hum. Gene Ther. (2001)
- Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function. Bott-Flügel, L., Weig, H.J., Knödler, M., Städele, C., Moretti, A., Laugwitz, K.L., Seyfarth, M. J. Mol. Med. (2005)
- Efficient cloning of ascomycete mating type genes by PCR amplification of the conserved MAT HMG Box. Arie, T., Christiansen, S.K., Yoder, O.C., Turgeon, B.G. Fungal Genet. Biol. (1996)
- Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N-ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum. Weidenhaupt, M., Bruckert, F., Louwagie, M., Garin, J., Satre, M. Eur. J. Biochem. (2000)
- Baculovirus p35 increases pancreatic beta-cell resistance to apoptosis. Hollander, K., Bar-Chen, M., Efrat, S. Biochem. Biophys. Res. Commun. (2005)