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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 299 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of CDK5R1 Brain levels of CDK5 activator p25 are not increased in Alzheimer... supranuclear palsy( PSP ), frontotemporal dementia( FTD). Involvement of Cdk5/ p25 in digoxin- triggered.... Psychiatry related information on CDK5R1 Mutations and novel polymorphisms in coding regions and UTRs of CDK5... / Synonyms: CDK5 activator 1; CDK5P35; CDK5R
Homo sapiens
Gene: ... Disease relevance of CDK5 CDK5 represents an attractive pharmacological target as its deregulation... diseases, ischemia, and amyotrophic lateral sclerosis. Furthermore, reduced expression of CDK5/ p35 in the epidermis might be involved in the pathogenesis of psoriasis. Involvement of Cdk5/ p25 in digoxin- triggered...
Rattus norvegicus
Gene: ... Disease relevance of Cdk5 Deregulation of the Cdk5 enzymatic activity was found to associate... and activity of Cdk5, and this reduction was inhibited by pre- treatment with ASA. Recently, the toxicity of Abeta to neurons was shown to be dependent upon the activation of cyclin- dependent kinase 5( Cdk5...
Mus musculus
Gene: ... Disease relevance of Cdk5 In contrast, the excitotoxic component of ischemia/ hypoxia is predominately regulated by Cdk5 and its activator p35, components of a cyclin- dependent kinase complex associated with neuronal development. We conclude that Cdk5 may be the principal protein kinase responsible...
Drosophila melanogaster
Gene: ... Disease relevance of Cdk5alpha Constitutive over- expression of dCdk5alpha in transgenic flies... conditions. High impact information on Cdk5alpha Cell death, but not morphological changes, was blocked... of Ckd5/ Cdk5alpha is essential for neurite outgrowth during neuronal differentiation and possibly also... / Synonyms: Cdk5a; dCdk5alpha
Homo sapiens
Gene: ... Disease relevance of CDK5RAP1 METHODS: The COS- 1 cells and Escherichia coli were used to express... on CDK5RAP1 The C42 enzyme can be replaced by trypsin, so that bridging units may consist of C3+ C42, C5... the activation of Cdk5 by Nck5a. When tonsil lymphocytes, which contain between 30 and 60% of CR1- bearing B... / Synonyms: CDK5 activator-binding protein C42; CDK5 regulatory subunit-associated protein 1
Mus musculus
Gene: ... Disease relevance of Cdk5rap3 In vivo treatment with free or nanoparticle- bound colistin did.... High impact information on Cdk5rap3 The enzyme kinetics of the glutathione( GSH) conjugation... CBP and the CDK5 activator binding protein- C53. Reporter assays demonstrated that C53 had little... / Synonyms: CDK5 regulatory subunit-associated protein 3
Homo sapiens
Gene: ... Disease relevance of CDK5RAP3 In this study, we analyzed the presence of antibodies directed to HIV...) utilizing the grid- blot method in PBMC cultures of 52 mother- child pairs. High impact information on CDK5... cells. C53 was originally identified as a Cdk5 activator p35- binding protein and a caspase substrate... / Synonyms: CDK5 activator-binding protein C53; CDK5 regulatory subunit-associated protein 3
Homo sapiens
Gene: ... Disease relevance of CDK5RAP2 Transient response to imatinib in a chronic eosinophilic leukemia associated with ins( 9; 4 )( q33; q12q25) and a CDK5RAP2- PDGFRA fusion gene. Despite achieving complete... leukemia that was characterized by a normal karyotype, absence of detectable CDK5RAP2- PDGFRA m... / Synonyms: CDK5 activator-binding protein C48; CDK5 regulatory subunit-associated protein 2
Homo sapiens
Gene: ... Disease relevance of CDK5R2 P39 immunoreactivity in glial cytoplasmic inclusions in brains... information on CDK5R2 Using the myeloid cell line P39, we show that ATRA disturbs mitochondrial functional... the neuronal Cdk5 activator isoform( p39nck5ai ), showed a high degree of sequence similarity to p35nck5a... / Synonyms: CDK5 activator 2

 

 
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