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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 36 documents. Results 1 - 10.

Sus scrofa
Gene: ... High impact information on DIO2 Thyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein- 1 in brown adipocytes. Anatomical context of DIO2 Type II iodothyronine deiodinase mRNA, its activity, and uncoupling protein- 1 mRNA in cultured...
Bos taurus
Gene: ... High impact information on DIO2 Molecular cloning, expression and radiation hybrid mapping of the bovine deiodinase type II( DIO2) and deiodinase type III( DIO3) genes. Expression patterns of the three deiodinase isoforms were similar for deiodinase type I( DIO1) and DIO2 to those observed in other species...
Gallus gallus
Gene: ... Disease relevance of DIO2 These results indicate that the inadequate expression of DIO2 in the growth plates contributes to the pathogenesis of TD in broilers and that TD is a tissue- specific hypothyroidism. High impact information on DIO2 Type II iodothyronine deiodinase protein in chicken choroid...
Mus musculus
Gene: ... , UCP1 mRNA, and O( 2) consumption are all reduced due to impaired cAMP generation. The sustained Dio2...Disease relevance of Dio2 Here we report that despite a normal plasma 3, 5, 3 '- triiodothyronine( T3) concentration, cold- exposed mice with targeted disruption of the Dio2 gene( Dio2 (-/-)) become...
Xenopus laevis
Gene: ... High impact information on dio2- A This difference is because of the conversion of T4 to T3 in target cells of the tadpole catalyzed by the enzyme type II iodothyronine deiodinase( D2) and the local effect( cell autonomy) of this activity. Timing of metamorphosis and the onset of the negative feedback...
Rattus norvegicus
Gene: ... Disease relevance of Dio2 Increase in type II 5' deiodinase activity and the number of binding... the cellular T3 levels within a narrow limit. High impact information on Dio2 These data show that myosin V... deiodinase mRNA followed by the increase in deiodinase activity. Biological context of Dio2 Evidence...
Homo sapiens
Gene: ... and DIO2 were underexpressed in nearly all papillary thyroid carcinomas. We conclude that intrathyroidal T...Disease relevance of DIO2 We performed molecular scanning of the human type 2 deiodinase( DIO2... 67% in thyrotoxic patients. Psychiatry related information on DIO2 Positive association of the DIO2...
Homo sapiens
Gene
MeSH term: ... disruption of the Dio2 gene( Dio2 (-/-)) become hypothermic due to impaired BAT thermogenesis and survive... lipoprotein lipase activity increased in all patients, from 3. 8 +/- 1. 1 to 7. 1 +/- 1. 6 neq of free fatty... progressed. In all four subjects studied before correction of weight loss, the response to hypertonic saline...
MeSH term: ... . Molecular cloning, expression and radiation hybrid mapping of the bovine deiodinase type II( DIO2...

 

 
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