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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 62 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of E2f3 E2F3 loss has opposing effects on different pRB- deficient tumors... of E2F1 and E2F3 strongly evoked programmed cell death concomitant with cell cycle progression. High impact information on E2f3 This rescue appears to be cell autonomous since the inactivation of Rb and E2f... / Synonyms: E2F-3; E2F3b; E2f3a
Homo sapiens
Gene: ... Disease relevance of E2F3 When patients are stratified according to the maximum percentage of E2F3... .), there is an increasingly significant association between E2F3 staining and risk of death both for overall survival( P= 0. 0014) and for cause- specific survival( P= 0. 0004). In summary, our results suggest that DEK and E2F3... / Synonyms: E2F-3; Transcription factor E2F3
Arabidopsis thaliana
Gene: ... High impact information on E2F3 We examined the effect of E2F ectopically expressed in transgenic tobacco( Nicotiana tabacum) plants on growth and development using E2Fa( AtE2F3) and DPa from Arabidopsis. Both AtE2F1 and AtE2F3 were translocated to the nucleus and transactivate an E2F reporter gene when co... / Synonyms: E2F TRANSCRIPTION FACTOR-3 E2F3
MeSH term: ... to induce pituitary tumors, we generated transgenic mice expressing an inducible E2F3 protein... pituitary prolactin( PRL) cell hyperplasia in all animals after 9 and 12 weeks of treatment. Hyperplastic... lobe of the pituitary gland, liver, and germinal center of the white pulp of spleen, all tissues...
Mus musculus
Gene: ... cultures of P19 cells. E2F3 loss suppresses the development of the pituitary tumors that normally account... as a barrier to immortalization. Here we show that the E2f3 mutation completely suppresses both the inappropriate proliferation and the p53- dependent apoptosis arising in the Rb mutant embryos. E2F3 contributes...
Mus musculus
Gene: ... - dependent mechanism. Here we show that the E2f3 mutation completely suppresses both the inappropriate... was not different among the organ types, and immunohistochemistry revealed that all the organs expressed these two...
Mus musculus
Gene: ... not result in an onset of apoptosis whereas directed expression of E2F1 and E2F3 strongly evoked programmed..., E2f2, and E2f3 are also required for oncogene- mediated transformation of mouse embryonic... and E2F3. Other interactions of E2f2 In 12. 5 dpc embryos, E2F- 1, E2F- 2 and E2F- 5 are highly...
MeSH term: ... the role of E2F3 in vivo, we generated an E2f3 mutant mouse strain. A mutant mouse strain was generated... monoclonal anti- Iab antibodies. This suggests that all four genes are perinatally triggered at the level...
Pan troglodytes
Gene

 

 
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