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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 57 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of HDAC2 We show that the upregulation of HDAC2 in colorectal cancer occurred early at the polyp stage, was more robust and occurred more frequently than HDAC1. Although most HDAC2 is not phosphorylated in the breast cancer cells, HDAC2 bound to Sp1 and Sp3 and cross- linked to chromatin in situ...
Mus musculus
Gene: ... Disease relevance of Hdac2 In this study, we demonstrate that the histone deacetylases Hdac- 1 and Hdac- 2 are rapidly recruited to the insulin promoter in the mouse insulinoma cell line MIN6 when cells are switched from high to low glucose media. High impact information on Hdac2 Treatment of MIN6 cells...
Rattus norvegicus
Gene: ... High impact information on Hdac2 DNA methyltransferase 3b regulates nerve growth factor- induced differentiation of PC12 cells by recruiting histone deacetylase 2....
Gallus gallus
Gene: ... High impact information on HDAC2 Chicken histone deacetylase- 2 controls the amount of the IgM H... for the interaction with CAF- 1p48 and HDAC- 2 in vivo. In a chicken B cell line, DT40, the disruption of HDAC2( chHDAC...) gene by 2D- PAGE analysis. Anatomical context of HDAC2 Ion- exchange( Q- Sepharose) and gel- exclusion...
Xenopus (Silurana) tropicalis
Gene: ... High impact information on hdac2 Distinct requirements for chromatin assembly in transcriptional... oocytes is regulated by phosphorylation. Biological context of hdac2 A major event in the assembly... shock protein gene expression during Xenopus development. Anatomical context of hdac2 Addition...
MeSH term: ... deacetylases, HDAC2, in sporadic carcinomas with microsatellite instability and in tumors arising...- induced skin tumors, but 70% of carcinomas from Pten +/- mice do not exhibit this mutation, and in all... of chemotherapeutic treatment for all tumors; for ovarian and small- cell lung carcinomas( SCLCs ), these levels were...
MeSH term: ... of Ashkenazi Jewish ancestry. High impact information on Frameshift Mutation The presence of the HDAC2 frameshift mutation causes a loss of HDAC2 protein expression and enzymatic activity and renders these cells... inhibitors. Here we report that although all nonsense and frameshift mutations that cause premature...
Homo sapiens
Gene: ... , and with purified maspin. We show that the upregulation of HDAC2 in colorectal cancer occurred early at the polyp... in the therapy of epilepsy and bipolar disorder. High impact information on HDAC1 The presence of the HDAC2 frameshift mutation causes a loss of HDAC2 protein expression and enzymatic activity and renders these cells...
MeSH term: ... . In conclusion, we show that overexpression of HDAC2 in glucocorticoid- insensitive alveolar macrophages from... leukocytes all phagocytize L. pneumophila by this unusual process, termed" coiling phagocytosis...
Chemical compound: ... acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65- HAT... ventricular interstitial collagen( 2. 5- fold vs control, P< 0. 01 vs all groups ); other steroid treatments...

 

 
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