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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 1187 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Igf1 Igf1 promotes longitudinal bone growth by insulin- like actions augmenting chondrocyte hypertrophy. Igf1 -/- kidney, spleen and liver are slightly but significantly increased in size relative to the degree of reduction in Igf1 -/- body weight. Simian virus 40 large tumor... / Synonyms: Igf-1
Homo sapiens
Gene: ... Disease relevance of IGF1 Retrovirally mediated transmission of mVL30 RNA to human tumor cells induced several genes, including oncogenes, which also are induced by IGF1, and promoted metastasis. Insulin- like growth factor 1( IGF1) binding sites were characterized in breast cancer. Several... / Synonyms: IGF1A
Rattus norvegicus
Gene: ... Disease relevance of Igf1 These data support the hypothesis that hypoxia regulation of IGFBP- 1 may..., stimulation of mitogen- activated protein( MAP) kinase via the IGF1 receptor and the Gi- coupled receptor...- induced muscle atrophy. Psychiatry related information on Igf1 We tested the hypothesis that low nephron... / Synonyms: Igf-1
Homo sapiens
Gene: ... MDA- 231BO cell line by activating the type I IGF receptor( IGF1R). Transcripts for all three...Disease relevance of IGF1R A single patient with Beckwith- Wiedemann Syndrome( BWS) demonstrated monoallelic expression of the maternally derived IGF1R allele in normal kidney, associated Wilms' tumour...
Mus musculus
Gene: ... Disease relevance of Igf1r In contrast, null mutants for the Igf1r gene die invariably at birth of respiratory failure and exhibit a more severe growth deficiency( 45% normal size). Igf- 1 (-/-)/ Igf1r (-/-) double mutants did not differ in phenotype from Igf1r (-/-) single mutants, while in Igf- 2 (-)/ Igf1r... / Synonyms: IGF-1R
Gallus gallus
Gene: ... Disease relevance of IGF1 Significant associations( P< 0. 0125) were found between VDR and bone mineral content of the humerus at 35 weeks of age; between IGF1 and SPP1 and 5- week body weight; and between INS and 55- week body weight. CONCLUSIONS: The elevated IGFBP levels and reduced IGF- 1 levels... / Synonyms: IGF-1
Mus musculus
Gene: ... High impact information on Igf1sl1 Functional isolation of the Igf1sl1 QTL on Chr 6 for IGF- 1 in B6. C3H- 6 congenic mice demonstrated effects on both the IGF- 1 and BMD phenotypes....
Danio rerio
Gene: ... , all indicated that the zebrafish have more than one IGF- 1 gene. Tilapia( Oreochromis mossambicus) IGF...Disease relevance of igf1 Hypoxia strongly induced the expression of insulin- like growth factor... edema. High impact information on igf1 When tested in vitro with cultured zebrafish embryonic cells... / Synonyms: IGF-1; IGF-1L; IGF-1a
Bos taurus
Gene: ... Disease relevance of IGF1 The components of the insulin- like growth factor( IGF) axis... information on IGF1 Food deprivation for nearly 3 d decreased the levels of serum IGF- I by 63%( P< 0. 01..., transforming growth factor- beta( TGF- beta) and insulin- like growth factor- 1( IGF- 1 ), cytokines which... / Synonyms: IGF-1
Rattus norvegicus
Gene: ... Disease relevance of Igf1r Because the IGF- I receptor is able to transduce mitogenic signals... that decreased Hsp60 expression and subsequent decline of IGF- 1R signaling may be a fundamental mechanism.... Psychiatry related information on Igf1r IGF- I receptor mRNA abundance was not significantly different...


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