Gene Review:
Igf1r - insulin-like growth factor 1 receptor
Rattus norvegicus
Synonyms:
IGF-I receptor, IGFIRC, Igfr1, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, ...
- Experimental diabetes increases insulinlike growth factor I and II receptor concentration and gene expression in kidney. Werner, H., Shen-Orr, Z., Stannard, B., Burguera, B., Roberts, C.T., LeRoith, D. Diabetes (1990)
- Hsp10 and Hsp60 suppress ubiquitination of insulin-like growth factor-1 receptor and augment insulin-like growth factor-1 receptor signaling in cardiac muscle: implications on decreased myocardial protection in diabetic cardiomyopathy. Shan, Y.X., Yang, T.L., Mestril, R., Wang, P.H. J. Biol. Chem. (2003)
- Upregulation of cardiac insulin-like growth factor-I receptor by ACE inhibition after myocardial infarction: potential role in remodeling. Dean, R.G., Bach, L.A., Burrell, L.M. J. Histochem. Cytochem. (2003)
- Expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor and its intervention by interleukin-10 in experimental hepatic fibrosis. Wang, X.Z., Chen, Z.X., Zhang, L.J., Chen, Y.X., Li, D., Chen, F.L., Huang, Y.H. World J. Gastroenterol. (2003)
- Effect of testosterone on insulin-like growth factor-I (IGF-I) and IGF-I receptor gene expression in the hypophysectomized rat. Phillip, M., Palese, T., Hernandez, E.R., Roberts, C.T., LeRoith, D., Kowarski, A.A. Endocrinology (1992)
- Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation. Role of specific intracellular signaling pathways. Giorgino, F., Smith, R.J. J. Clin. Invest. (1995)
- Cellular distribution of insulin-degrading enzyme gene expression. Comparison with insulin and insulin-like growth factor receptors. Bondy, C.A., Zhou, J., Chin, E., Reinhardt, R.R., Ding, L., Roth, R.A. J. Clin. Invest. (1994)
- Extracellular matrix composition influences insulinlike growth factor I receptor expression in rat IEC-18 cells. Benya, R.V., Duncan, M.D., Mishra, L., Bass, B.L., Voyles, N.R., Korman, L.Y. Gastroenterology (1993)
- Insulin-like growth factor-I receptor and binding proteins in rat kidney after nephron loss. Hise, M.K., Lahn, J.S., Shao, Z.M., Mantzouris, N.M., Fontana, J.A. J. Am. Soc. Nephrol. (1993)
- Participation of growth factor signal transduction pathways in estradiol facilitation of female reproductive behavior. Etgen, A.M., Acosta-Martinez, M. Endocrinology (2003)
- Insulin-like growth factor I administration in young rats with acute renal failure. Medina, A., Fernández-Fuente, M., Carbajo-Pérez, E., Santos, F., Amil, B., Rodríguez, J., Crespo, M. Pediatr. Nephrol. (2002)
- IGF1 receptor expression protects against microenvironmental stress found in the solid tumor. Peretz, S., Kim, C., Rockwell, S., Baserga, R., Glazer, P.M. Radiat. Res. (2002)
- Insulin-like Growth Factors and Their Binding Proteins Define Specific Phases of Myometrial Differentiation During Pregnancy in the Rat. Shynlova, O., Tsui, P., Dorogin, A., Langille, B.L., Lye, S.J. Biol. Reprod. (2007)
- Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos. Kedia, N., Gill-Sharma, M.K., Parte, P., Juneja, H.S., Balasinor, N. Mol. Reprod. Dev. (2004)
- Anatomical relationships in the patterns of insulin-like growth factor (IGF)-I, IGF binding protein-1, and IGF-I receptor gene expression in the rat kidney. Chin, E., Zhou, J., Bondy, C. Endocrinology (1992)
- Growth hormone action on proliferation and differentiation of cerebral cortical cells from fetal rat. Ajo, R., Cacicedo, L., Navarro, C., Sánchez-Franco, F. Endocrinology (2003)
- Double-stranded ribonucleic acid decreases C6 rat glioma cell numbers: effects on insulin-like growth factor I gene expression and action. Chacko, M.S., Adamo, M.L. Endocrinology (2000)
- Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes. Hallak, H., Moehren, G., Tang, J., Kaou, M., Addas, M., Hoek, J.B., Rubin, R. Hepatology (2002)
- Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I. El-Shewy, H.M., Kelly, F.L., Barki-Harrington, L., Luttrell, L.M. Mol. Endocrinol. (2004)
- In vivo regulation of granulosa cell somatomedin-C/insulin-like growth factor I receptors. Adashi, E.Y., Resnick, C.E., Hernandez, E.R., Svoboda, M.E., Van Wyk, J.J. Endocrinology (1988)
- Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells. Raile, K., Klammt, J., Laue, S., Garten, A., Blüher, M., Kralisch, S., Klöting, N., Kiess, W. Diabetologia (2005)
- Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Kulik, G., Klippel, A., Weber, M.J. Mol. Cell. Biol. (1997)
- Estradiol and progesterone regulate the expression of insulin-like growth factor-I receptor and insulin-like growth factor binding protein-2 in the hypothalamus of adult female rats. Cardona-G¿omez, G.P., Chowen, J.A., Garcia-Segura, L.M. J. Neurobiol. (2000)
- Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling. Garcia-Galloway, E., Arango, C., Pons, S., Torres-Aleman, I. Mol. Cell. Neurosci. (2003)
- Insulin-like growth factor-I receptor and estrogen receptor crosstalk mediates hormone-induced neurite outgrowth in PC12 cells. Topalli, I., Etgen, A.M. Brain Res. (2004)
- Effect of transforming growth factor-beta on the insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes. Tsukazaki, T., Usa, T., Matsumoto, T., Enomoto, H., Ohtsuru, A., Namba, H., Iwasaki, K., Yamashita, S. Exp. Cell Res. (1994)
- Transcriptional regulation of the insulin-like growth factor-I receptor gene: evidence for protein kinase C-dependent and -independent pathways. Du, J., Meng, X.P., Delafontaine, P. Endocrinology (1996)
- Insulin-like growth factor (IGF) binding proteins modulate the glucocorticoid-dependent biological effects of IGF-II in cultured fetal rat hepatocytes. Menuelle, P., Babajko, S., Plas, C. Endocrinology (1999)
- Insulin-like growth factor I: a mitogen for rat Schwann cells in the presence of elevated levels of cyclic AMP. Schumacher, M., Jung-Testas, I., Robel, P., Baulieu, E.E. Glia (1993)
- Role of receptors for epidermal growth factor and insulin-like growth factors I and II in the differentiation of rat mammary glands from lactogenesis I to lactogenesis II. Bussmann, L.E., Bussmann, I.M., Charreau, E.H. J. Reprod. Fertil. (1996)
- Cortisol represses insulin-like growth factor II receptor transcription in skeletal cell cultures. Rydziel, S., Canalis, E. Endocrinology (1995)
- Castration-induced apoptosis in the rat ventral prostate is associated with increased expression of genes encoding insulin-like growth factor binding proteins 2,3,4 and 5. Nickerson, T., Pollak, M., Huynh, H. Endocrinology (1998)